Siglec-2/CD22 Products
Siglec-2 (sialic acid binding Ig-like lectin 2), also known as CD22, is a 130-140 kDa type I transmembrane glycoprotein with seven Ig-like domains in the extracellular region and three ITIM motifs in its cytoplasmic region. Alternate splicing generates an additional isoform that lacks the third and fourth Ig-like domains. Siglec-2 is expressed on B cells, preferentially binds alpha 2-6 linked sialic glycans including CD45 and mediates B cell - B cell interactions. Phosphorylation of Tyr822 within one of the ITIMs is important for Siglec-2 signal transduction through its association with the kinases Lyn, PI 3-Kinase p85 alpha, and SYK.
59 results for "Siglec-2/CD22" in Products
59 results for "Siglec-2/CD22" in Products
Siglec-2/CD22 Products
Siglec-2 (sialic acid binding Ig-like lectin 2), also known as CD22, is a 130-140 kDa type I transmembrane glycoprotein with seven Ig-like domains in the extracellular region and three ITIM motifs in its cytoplasmic region. Alternate splicing generates an additional isoform that lacks the third and fourth Ig-like domains. Siglec-2 is expressed on B cells, preferentially binds alpha 2-6 linked sialic glycans including CD45 and mediates B cell - B cell interactions. Phosphorylation of Tyr822 within one of the ITIMs is important for Siglec-2 signal transduction through its association with the kinases Lyn, PI 3-Kinase p85 alpha, and SYK.
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC, Neut |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #308501 |
| Applications: | Flow |
| Source: | NS0 |
| Accession #: | P35329 |
| Applications: | BA |
| Reactivity: | Human, Mouse, Rat, Canine, Monkey |
| Details: | Mouse IgG1 Monoclonal Clone #OTI1F12 |
| Applications: | WB, ICC/IF |
![Western Blot: Siglec-2/CD22 Antibody (OTI1F12) [NBP2-46125]](https://resources.bio-techne.com/images/products/Siglec-2-CD22-Antibody-1F12-Western-Blot-NBP2-46125-img0003.jpg "Western Blot: Siglec-2/CD22 Antibody (OTI1F12) [NBP2-46125]")
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #308501 |
| Applications: | WB, Flow, CyTOF-ready |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #308501 |
| Applications: | Flow |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #308501 |
| Applications: | Flow |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #308501 |
| Applications: | Flow |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #308501 |
| Applications: | Flow |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #308501 |
| Applications: | Flow |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #308501 |
| Applications: | Flow |
| Reactivity: | Mouse |
| Details: | Rat IgG2A Monoclonal Clone #308501 |
| Applications: | WB, Flow, CyTOF-ready |
| Reactivity: | Human, Mouse, Rat, Canine, Monkey |
| Details: | Mouse IgG1 Monoclonal Clone #OTI1F12 |
| Applications: | WB, ICC/IF |
| Reactivity: | Human, Mouse, Rat, Canine, Monkey |
| Details: | Mouse IgG1 Monoclonal Clone #OTI1F12 |
| Applications: | WB, ICC/IF |
| Reactivity: | Human, Mouse, Rat, Canine, Monkey |
| Details: | Mouse IgG1 Monoclonal Clone #OTI1F12 |
| Applications: | WB, ICC/IF |
| Reactivity: | Mouse |
| Details: | Rat IgG2A Monoclonal Clone #308501 |
| Applications: | WB, Flow, CyTOF-ready |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 kappa Monoclonal Clone #MYG13 |
| Applications: | Flow |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 kappa Monoclonal Clone #MYG13 |
| Applications: | Flow |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 kappa Monoclonal Clone #MYG13 |
| Applications: | Flow |
| Reactivity: | Mouse |
| Details: | Rat IgG2A Monoclonal Clone #308501 |
| Applications: | WB, Flow, CyTOF-ready |
| Reactivity: | Mouse |
| Details: | Rat IgG2A Monoclonal Clone #308501 |
| Applications: | WB, Flow, CyTOF-ready |
| Reactivity: | Mouse |
| Details: | Rat IgG2A Monoclonal Clone #308501 |
| Applications: | Flow |
| Reactivity: | Mouse |
| Details: | Rat IgG2A Monoclonal Clone #308501 |
| Applications: | WB, Flow, CyTOF-ready |
| Reactivity: | Mouse |
| Details: | Rat IgG2A Monoclonal Clone #308501 |
| Applications: | WB, Flow, CyTOF-ready |
| Reactivity: | Mouse |
| Details: | Rat IgG2A Monoclonal Clone #308501 |
| Applications: | WB, Flow, CyTOF-ready |