24 results for "Smoothened" in Products
Smoothened Products
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #1D9 |
| Applications: | WB, ELISA |
![Western Blot: Smoothened Antibody (1D9) [H00006608-M11]](https://resources.bio-techne.com/images/products/Smoothened-Antibody-1D9-Western-Blot-H00006608-M11-img0002.jpg "Western Blot: Smoothened Antibody (1D9) [H00006608-M11]")
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #1015418 |
| Applications: | IHC |
Applications: IHC, ICC/IF
Reactivity:
Human,
Mouse,
Rat,
Canine,
Monkey, +6 More
| Reactivity: | Human, Mouse, Rat, Canine, Monkey, +6 More |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ICC/IF |
![Immunohistochemistry-Paraffin: Smoothened Antibody - BSA Free [NLS2666]](https://resources.bio-techne.com/images/products/Smoothened-Antibody-Immunohistochemistry-Paraffin-NLS2666-img0003.jpg "Immunohistochemistry-Paraffin: Smoothened Antibody - BSA Free [NLS2666]")
Applications: IHC, WB, ELISA
Reactivity:
Human,
Mouse,
Rat
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA |
![Western Blot: Smoothened Antibody [NBP3-06699]](https://resources.bio-techne.com/images/products/Smoothened-Antibody-Western-Blot-NBP3-06699-img0003.jpg "Western Blot: Smoothened Antibody [NBP3-06699]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
| Applications: | WB, ELISA, MA, AP, PAGE |
| Applications: | WB, ELISA, MA, AP, PAGE |
![SDS-PAGE: Recombinant Human Smoothened GST (N-Term) Protein [H00006608-Q01]](https://resources.bio-techne.com/images/products/qc_test-H00006608-Q01-1.jpg "SDS-PAGE: Recombinant Human Smoothened GST (N-Term) Protein [H00006608-Q01]")
| Applications: | WB, ELISA, MA, AP |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
| Applications: | AP |
| Applications: | WB |
![Western Blot: Smoothened Overexpression Lysate [NBP2-10451]](https://resources.bio-techne.com/images/products/Smoothened-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-10451-img0001.jpg "Western Blot: Smoothened Overexpression Lysate [NBP2-10451]")
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #3D10 |
| Applications: | WB, ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #3E5 |
| Applications: | WB, ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #2F8 |
| Applications: | ELISA |
![ELISA: Smoothened Antibody (2F8) [H00006608-M07]](https://resources.bio-techne.com/images/products/Smoothened-Antibody-2F8-ELISA-H00006608-M07-img0001.jpg "ELISA: Smoothened Antibody (2F8) [H00006608-M07]")
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #3G8 |
| Applications: | ELISA |
![ELISA: Smoothened Antibody (3G8) [H00006608-M06]](https://resources.bio-techne.com/images/products/Smoothened-Antibody-3G8-ELISA-H00006608-M06-img0001.jpg "ELISA: Smoothened Antibody (3G8) [H00006608-M06]")
Potent Smoothened receptor antagonist
| Chemical Name: | rel-N-[6-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-3-pyridinyl]-2-methyl-4'-(trifluoromethoxy)[1,1'-biphenyl]-3-carboxamide |
| Purity: | ≥98% (HPLC) |
High affinity and selective Smoothened (Smo) receptor antagonist
| Chemical Name: | 1-[4-(5'-Chloro-3,5-dimethyl[2,4'-bipyridin]-2'-yl-1-piperazinyl]-3-(methylsulfonyl)-1-propanone hydrochloride |
| Purity: | ≥98% (HPLC) |
Inhibitor of Hedgehog (Hh) signaling
| Chemical Name: | (2'R,3S,3'R,3'aS,6'S,6aS,6bS,7'aR,11aS,11bR)-1,2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11,11a,11b-Octadecahydro-3',6',10,11b-tetramethylspiro[9H-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-3-ol |
| Purity: | ≥97% (HPLC) |
SMO antagonist; acts at different binding site to cyclopamine (Cat No. 1623)
| Chemical Name: | 4-[4-[4-[4-[[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one |
| Purity: | ≥99% (HPLC) |
Potent Smo antagonist
| Alternate Names: | glasdegib,PF-913 |
| Chemical Name: | 1-((2R,4R)-2-(1H-Benzimidazol-2-yl)-1-methylpiperidin-4-yl)-3-(4-cyanophenyl)urea maleate salt |
| Purity: | ≥98% (HPLC) |
Potent and high affinity Smo receptor agonist
| Chemical Name: | 3-Chloro-4,7-difluoro-N-[trans-4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]benzo[b]thiophene-2-carboxamide |
| Purity: | ≥98% (HPLC) |
Dihydrochloride salt of SAG; Smo receptor agonist
| Chemical Name: | 3-Chloro-N-[trans-4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]benzo[b]thiophene-2-carboxamide dihydrochloride |
| Purity: | ≥98% (HPLC) |
Potent Smo antagonist
| Chemical Name: | N,N'-1,4-Phenylenebis[2,5-dichlorobenzamide] |
| Purity: | ≥99% (HPLC) |
