Thrombomodulin/BDCA-3 Products
Thrombomodulin (TM), also known as CD141 and BDCA3, is a transmembrane expressed on vascular endothelial cells (EC), arterial smooth muscle cells, monocytes, and macrophages. It binds Thrombin and enhances the Thrombin-mediated activation of the anti-coagulant Protein C and the anti-fibrinolytic TAFI/Carboxypeptidase B2. Thrombomodulin also inhibits the ability of Thrombin to activate several pro-coagulant proteins (e.g. Fibrinogen, Factor V, Factor XIII, PAR-1). Thrombomodulin exerts multiple anti-inflammatory effects and reduces the severity of disease involving chronic inflammation. In cancer, Thrombomodulin suppresses tumor angiogenesis, growth, and epithelial-mesenchymal transition. Soluble fragments of Thrombomodulin are elevated in the serum, urine, and synovial fluid during coagulation disorders, inflammation, and organ failure.
236 results for "Thrombomodulin/BDCA-3" in Products
236 results for "Thrombomodulin/BDCA-3" in Products
Thrombomodulin/BDCA-3 Products
Thrombomodulin (TM), also known as CD141 and BDCA3, is a transmembrane expressed on vascular endothelial cells (EC), arterial smooth muscle cells, monocytes, and macrophages. It binds Thrombin and enhances the Thrombin-mediated activation of the anti-coagulant Protein C and the anti-fibrinolytic TAFI/Carboxypeptidase B2. Thrombomodulin also inhibits the ability of Thrombin to activate several pro-coagulant proteins (e.g. Fibrinogen, Factor V, Factor XIII, PAR-1). Thrombomodulin exerts multiple anti-inflammatory effects and reduces the severity of disease involving chronic inflammation. In cancer, Thrombomodulin suppresses tumor angiogenesis, growth, and epithelial-mesenchymal transition. Soluble fragments of Thrombomodulin are elevated in the serum, urine, and synovial fluid during coagulation disorders, inflammation, and organ failure.
Sensitivity: | 19.1 pg/mL |
Applications: | ELISA |
Assay Range: | 46.9 - 3,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Urine) |
Sensitivity: | 27 pg/mL |
Applications: | ELISA |
Assay Range: | 62.5 - 4,000 pg/mL (Cell Culture Supernates, Cell Lysates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma, Urine) |
Reactivity: | Mouse |
Details: | Goat IgG Polyclonal |
Applications: | WB, Flow, IHC, IP, CyTOF-ready, +1 More |
Reactivity: | Mouse |
Details: | Rat IgG2b Monoclonal Clone #461714 |
Applications: | WB, Flow, IHC, CyTOF-ready, ICC |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #501733 |
Applications: | Flow, IHC, CyTOF-ready |
Reactivity: | Human |
Details: | Mouse IgG2A Monoclonal Clone #QBEND/40 |
Applications: | IHC, ICC/IF, Flow, MS |
Assay Range: | 31.2 - 2,000 pg/mL |
Applications: | ELISA |
Reactivity: | Mouse |
Details: | Rat IgG2b Monoclonal Clone #461714 |
Applications: | Flow |
Reactivity: | Human |
Details: | Sheep IgG Polyclonal |
Applications: | WB, Flow, IHC, IP, CyTOF-ready |
Reactivity: | Mouse |
Details: | Rat IgG2b Monoclonal Clone #461714 |
Applications: | Flow |
Source: | NS0 |
Accession #: | P07204 |
Applications: | EnzAct |
Source: | NS0 |
Accession #: | P15306 |
Applications: | EnzAct |
Reactivity: | Human, Mouse |
Details: | Mouse IgG1 Lambda Monoclonal Clone #6C8.2F9 |
Applications: | IHC, WB, Flow |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ICC/IF |
Reactivity: | Mouse |
Details: | Goat IgG Polyclonal |
Applications: | WB, Flow |
Reactivity: | Mouse |
Details: | Rat IgG2b Monoclonal Clone #461714 |
Applications: | Flow |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #501733 |
Applications: | Flow |
For use with catalog number DTHBD0
Applications: | ELISA, Ctrl |
Reactivity: | Human |
Details: | Mouse IgG2a Monoclonal Clone #501727 |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #501733 |
Applications: | Flow |
Reactivity: | Human |
Details: | Mouse IgG2b Kappa Monoclonal Clone #THBD/1591 |
Applications: | IHC, WB, ELISA, MA |
Reactivity: | Human |
Details: | Mouse IgG2a Monoclonal Clone #501727 |
Applications: | WB, IP |
Reactivity: | Human |
Details: | Mouse IgG2a Kappa Monoclonal Clone #THBD/1782 |
Applications: | IHC, ELISA, MA |
Reactivity: | Mouse |
Details: | Rat IgG1 Monoclonal Clone #4D8.2C6 |
Applications: | IHC, WB, Flow |