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TIM-1/KIM-1/HAVCR Products

TIM-1 (T cell immunoglobulin and mucin domain 1), also known as KIM-1 and HAVcr1, is expressed on many immune cell types and epithelial cells. It binds to phosphatidylserine (PS), LMIR5/CD300b, TIM-1 (homophilic), TIM-4, IgA, and the glycoproteins of a number of enveloped viruses. Its interaction with PS enables TIM-1 to mediate the phagocytosis and clearance of apoptotic cells. TIM-1 signaling costimulates T cell activation and enhances Th2 cytokine production. TIM-1 serves as a cellular entry receptor for hepatitis A virus, Ebolavirus and Marburgvirus. Polymorphisms are associated with susceptibility to atopy, autoimmunity, and severe hepatitis A virus infection in humans. A soluble form of TIM-1 is elevated in the urine during nephropathy.

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310 results for "TIM-1/KIM-1/HAVCR" in Products

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310 results for "TIM-1/KIM-1/HAVCR" in Products

TIM-1/KIM-1/HAVCR Products

TIM-1 (T cell immunoglobulin and mucin domain 1), also known as KIM-1 and HAVcr1, is expressed on many immune cell types and epithelial cells. It binds to phosphatidylserine (PS), LMIR5/CD300b, TIM-1 (homophilic), TIM-4, IgA, and the glycoproteins of a number of enveloped viruses. Its interaction with PS enables TIM-1 to mediate the phagocytosis and clearance of apoptotic cells. TIM-1 signaling costimulates T cell activation and enhances Th2 cytokine production. TIM-1 serves as a cellular entry receptor for hepatitis A virus, Ebolavirus and Marburgvirus. Polymorphisms are associated with susceptibility to atopy, autoimmunity, and severe hepatitis A virus infection in humans. A soluble form of TIM-1 is elevated in the urine during nephropathy.

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Applications: WB
Reactivity: Mouse
Applications: WB, IHC, Dual ISH-IHC
Reactivity: Human
Applications: WB, IHC
Reactivity: Rat
Applications: Simple Plex

Simple Plex TIM-1/KIM-1/HAVCR assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.

Applications: WB, Flow, IHC, CyTOF-ready
Reactivity: Human

Clone 219211 was used by HLDA to establish CD designation

Applications: IHC, WB, ELISA, ICC/IF, KD
Reactivity: Human, Mouse, Rat, Porcine
Applications: WB, Flow
Reactivity: Mouse
Applications: Simple Plex

Simple Plex Mouse TIM-1/KIM-1/HAVCR assay kit for use on Ella instrument. Contains cartridge, sample diluent SD09, and wash buffer.

Applications: Simple Plex

Simple Plex Rat TIM-1/KIM-1/HAVCR assay kit for use on Ella instrument. Contains cartridge, sample diluent SD09, and wash buffer.

Applications: WB
Reactivity: Human

This protein is in the process of being discontinued.

Applications: WB
Reactivity: Mouse
Applications: IHC, WB, ICC/IF
Reactivity: Human, Mouse, Rat
Applications: BA, BA, Bind

Biotinylated

Applications: Flow, CyTOF-ready
Reactivity: Human
Applications: Flow, IHC, CyTOF-ready
Reactivity: Human

Recombinant Monoclonal Antibody.

Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies

Applications: Flow
Reactivity: Mouse
Applications: Flow
Reactivity: Human

Clone 219211 was used by HLDA to establish CD designation

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