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TIMP-2 Products

TIMP-2 (tissue inhibitor of metalloproteinases 2) is one of several TIMPs that form complexes with matrix metalloproteinases (MMPs) and inhibit their proteolytic activity. MMPs play an important role in many normal physiological processes such as embryonic development, morphogenesis, reproduction and tissue remodeling. They also participate in many pathological processes such as arthritis, cancer and cardiovascular disease. TIMP-2 binding to pro-MMP-2 is essential for the cell surface activation of pro-MMP-2 by active MMP-14 (MT1-MMP). TIMP-2 also suppresses EGF-mediated mitogenic signaling by short-circuiting EGF R activation.

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152 results for "TIMP-2" in Products

152 results for "TIMP-2" in Products

TIMP-2 Products

TIMP-2 (tissue inhibitor of metalloproteinases 2) is one of several TIMPs that form complexes with matrix metalloproteinases (MMPs) and inhibit their proteolytic activity. MMPs play an important role in many normal physiological processes such as embryonic development, morphogenesis, reproduction and tissue remodeling. They also participate in many pathological processes such as arthritis, cancer and cardiovascular disease. TIMP-2 binding to pro-MMP-2 is essential for the cell surface activation of pro-MMP-2 by active MMP-14 (MT1-MMP). TIMP-2 also suppresses EGF-mediated mitogenic signaling by short-circuiting EGF R activation.

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Applications: IHC
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: IHC
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: IHC
Reactivity: Human, Mouse, Rat, Bovine, Zebrafish, +2 More

Recombinant Monoclonal Antibody

Applications: IHC
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: IHC, ELISA, MA
Reactivity: Human
Applications: IHC
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: IHC, ELISA, MA
Reactivity: Human
Applications: IHC, ELISA, MA
Reactivity: Human
Applications: IHC
Reactivity: Human, Mouse, Rat, Bovine, Zebrafish, +2 More

Recombinant Monoclonal Antibody

Applications: Simple Plex

For the measurement of TIMP-1, TIMP-2, and TIMP-4. Earn double rewards for reviews

Applications: WB, IHC, Dual ISH-IHC, KO, Neut
Reactivity: Human, Mouse
Applications: Simple Plex

Simple Plex Human TIMP-2 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.

Applications: WB, IHC
Reactivity: Human

Contains 4 membranes-2 spotted in duplicate with antibodies against 35 different proteases and 2 spotted in duplicate with antibodies against 32 different protease inhibitors

Applications: IHC, WB, ICC/IF, Flow
Reactivity: Human, Mouse, Rat, Canine, Monkey
Applications: IHC, WB, ICC/IF
Reactivity: Human, Mouse
Applications: WB, IHC, KO
Reactivity: Human

Recombinant Monoclonal Antibody.

Applications: WB
Reactivity: Human
Applications: KO
Reactivity: Human
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