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TIMP-2 Products

TIMP-2 (tissue inhibitor of metalloproteinases 2) is one of several TIMPs that form complexes with matrix metalloproteinases (MMPs) and inhibit their proteolytic activity. MMPs play an important role in many normal physiological processes such as embryonic development, morphogenesis, reproduction and tissue remodeling. They also participate in many pathological processes such as arthritis, cancer and cardiovascular disease. TIMP-2 binding to pro-MMP-2 is essential for the cell surface activation of pro-MMP-2 by active MMP-14 (MT1-MMP). TIMP-2 also suppresses EGF-mediated mitogenic signaling by short-circuiting EGF R activation.

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253 results for "TIMP-2" in Products

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253 results for "TIMP-2" in Products

TIMP-2 Products

TIMP-2 (tissue inhibitor of metalloproteinases 2) is one of several TIMPs that form complexes with matrix metalloproteinases (MMPs) and inhibit their proteolytic activity. MMPs play an important role in many normal physiological processes such as embryonic development, morphogenesis, reproduction and tissue remodeling. They also participate in many pathological processes such as arthritis, cancer and cardiovascular disease. TIMP-2 binding to pro-MMP-2 is essential for the cell surface activation of pro-MMP-2 by active MMP-14 (MT1-MMP). TIMP-2 also suppresses EGF-mediated mitogenic signaling by short-circuiting EGF R activation.

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Applications: IHC
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: IHC
Reactivity: Human, Mouse, Rat, Bovine, Zebrafish, +2 More

Recombinant Monoclonal Antibody

Applications: IHC, ELISA, MA
Reactivity: Human
Applications: IHC
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: IHC
Reactivity: Human, Mouse, Rat, Bovine, Zebrafish, +2 More

Recombinant Monoclonal Antibody

Applications: IHC
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: IHC
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: IHC
Reactivity: Human, Mouse, Rat, Bovine, Zebrafish, +2 More

Recombinant Monoclonal Antibody

Applications: IHC
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: IHC
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: IHC, ELISA, MA
Reactivity: Human
Applications: IHC, ELISA, MA
Reactivity: Human
Applications: IHC, ELISA, MA
Reactivity: Human
Applications: IHC, ELISA, MA
Reactivity: Human
Applications: IHC
Reactivity: Human, Mouse, Rat, Bovine, Zebrafish, +2 More

Recombinant Monoclonal Antibody

Applications: IHC, ELISA, MA
Reactivity: Human
Applications: IHC
Reactivity: Human, Mouse, Rat, Bovine, Zebrafish, +2 More

Recombinant Monoclonal Antibody

Applications: IHC
Reactivity: Human, Mouse, Rat, Bovine, Zebrafish, +2 More

Recombinant Monoclonal Antibody

Applications: Simple Plex

For the measurement of TIMP-1, TIMP-2, and TIMP-4. Earn double rewards for reviews

Applications: Simple Plex

Simple Plex Human TIMP-2 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.

Applications: WB, IHC, Dual ISH-IHC, KO, Neut
Reactivity: Human, Mouse
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