UNC5H2/UNC5B Products
UNC5H2/UNC5B is a transmembrane molecule that mediates axon repulsion and growth cone collapse through interactions with Netrin, Neogenin, and FLRT3. Its association with DCC switches the DCC-Netrin-1 response from attraction to repulsion.
Outside the nervous system, UNC5H2 facilitates Netrin-1-mediated inhibition of capillary branching and leukocyte migration as well as Netrin-1-mediated promotion of osteoclast differentiation. It is downregulated in multiple cancers and inhibits tumor cell growth and invasion. It also plays a critical role in the development of atherosclerosis and the survival of renal tubular epithelial cells during acute kidney injury.
Products:
12 results for "UNC5H2/UNC5B" in Products
12 results for "UNC5H2/UNC5B" in Products
UNC5H2/UNC5B Products
UNC5H2/UNC5B is a transmembrane molecule that mediates axon repulsion and growth cone collapse through interactions with Netrin, Neogenin, and FLRT3. Its association with DCC switches the DCC-Netrin-1 response from attraction to repulsion.
Outside the nervous system, UNC5H2 facilitates Netrin-1-mediated inhibition of capillary branching and leukocyte migration as well as Netrin-1-mediated promotion of osteoclast differentiation. It is downregulated in multiple cancers and inhibits tumor cell growth and invasion. It also plays a critical role in the development of atherosclerosis and the survival of renal tubular epithelial cells during acute kidney injury.
Products:
Reactivity: | Rat |
Details: | Goat IgG Polyclonal |
Applications: | WB, IHC |
Reactivity: | Rat |
Details: | Mouse IgG2a Monoclonal Clone #187305 |
Applications: | WB |
Source: | NS0 |
Accession #: | O08722 |
Applications: | Bind |
Reactivity: | Rat |
Details: | Goat IgG Polyclonal |
Applications: | WB, IHC |
Reactivity: | Human, Mouse, Rat, Canine, Bovine |
Details: | Goat IgG Polyclonal |
Applications: | WB, ELISA |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC |
Reactivity: | Human |
Details: | Mouse IgG1 kappa Monoclonal Clone #1A9 |
Applications: | WB, ELISA |
Reactivity: | Human |
Details: | Goat IgG Polyclonal |
Applications: | WB, ELISA |
Applications: | AC |
Reactivity: | Human, Mouse |
Details: | Mouse IgG2B Monoclonal Clone #Guido-1 |
Applications: | Flow |
Source: | CHO |
Accession #: | Q8IZJ1 |
Applications: | BA |