4-1BB Ligand/TNFSF9 Antibody (BLR148J)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-14727

Recombinant Monoclonal
Novus Biologicals, part of Bio-Techne
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NBP3-14727
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Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit Clone # BLR148J

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all 4-1BB Ligand/TNFSF9 Antibodies »

Product Specifications

Immunogen

residues 71-254 (ECD)

Clonality

Monoclonal

Host

Rabbit

Scientific Data Images for 4-1BB Ligand/TNFSF9 Antibody (BLR148J)

Western Blot: 4-1BB Ligand/TNFSF9 Antibody (BLR148J) [NBP3-14727]

Western Blot: 4-1BB Ligand/TNFSF9 Antibody (BLR148J) [NBP3-14727]

Western Blot: 4-1BB Ligand/TNFSF9 Antibody (BLR148J) [NBP3-14727] - Whole cell lysate (25 ug) from HEK293T, Jurkat, Raji, and HeLa cells prepared using NETN lysis buffer. Rabbit anti-4-1BBL/CD137L/TNFSF9 recombinant monoclonal antibody used at 1:1000. HRP-conjugated goat anti-rabbit IgG. Chemiluminescence with an exposure time of 3 minutes. Lower Panel: Rabbit anti-COPB2 antibody.
Flow Cytometry: 4-1BB Ligand/TNFSF9 Antibody (BLR148J) [NBP3-14727]

Flow Cytometry: 4-1BB Ligand/TNFSF9 Antibody (BLR148J) [NBP3-14727]

Flow Cytometry: 4-1BB Ligand/TNFSF9 Antibody (BLR148J) [NBP3-14727] - Rabbit anti-4-1BBL/CD137L/TNFSF9 recombinant monoclonal or isotype control (unshaded). DyLight® 488-conjugated goat anti-rabbit IgG.

Applications for 4-1BB Ligand/TNFSF9 Antibody (BLR148J)

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

>95%

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 2 - 8 C / 1 year from date of receipt

Background: 4-1BB Ligand/TNFSF9

CD137 exists on the cell surface as a monomer with a molecular mass of 30 kDa and as a dimer of 55 kDa. Human and mouse CD137 share 60% amino acid identity. CD137 (4-1BB), a member of the tumor necrosis factor receptor superfamily, is a type I transmembrane glycoprotein expressed on the cell surface of activated splenic T cells and thymocytes. The functions of CD137 in T lymphocytes include regulating activation, proliferation and apoptosis. CD137 and CD28 are costimulatory molecules of T cell activation. Costimulatory molecules are important in initiating anti-tumor immune responses. CD137 plays an important role in regulating T-cell-dependent immune responses. Expression of CD137 correlates negatively with lymphocyte proliferation and positively with the degree of activation-induced cell death caused by mitogen over stimulation. In monocytes, CD137 induces activation, promotes adherence and prolongs survival.

Alternate Names

41BB Ligand, CD137L, TNFSF9

Gene Symbol

TNFSF9

Additional 4-1BB Ligand/TNFSF9 Products

Product Documents for 4-1BB Ligand/TNFSF9 Antibody (BLR148J)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for 4-1BB Ligand/TNFSF9 Antibody (BLR148J)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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