4-1BB/TNFRSF9/CD137 Antibody (OTI5H5) - Azide and BSA Free
Novus Biologicals, part of Bio-Techne | Catalog # NBP2-71035
![Western Blot: 4-1BB/TNFRSF9/CD137 Antibody (OTI5H5)Azide and BSA Free [NBP2-71035] Western Blot: 4-1BB/TNFRSF9/CD137 Antibody (OTI5H5)Azide and BSA Free [NBP2-71035]](https://resources.bio-techne.com/images/products/4-1BB-TNFRSF9-CD137-Antibody-OTI5H5-Azide-and-BSA-Free-Western-Blot-NBP2-71035-img0001.jpg)
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human
Applications
Western Blot
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG1 Clone # OTI5H5
Format
Azide and BSA Free
Concentration
LYOPH mg/ml
Product Specifications
Immunogen
Human recombinant protein fragment corresponding to amino acids 24-186 of human TNFRSF9 (NP_001552) produced in E.coli.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1
Scientific Data Images for 4-1BB/TNFRSF9/CD137 Antibody (OTI5H5) - Azide and BSA Free
Western Blot: 4-1BB/TNFRSF9/CD137 Antibody (OTI5H5)Azide and BSA Free [NBP2-71035]
Western Blot: 4-1BB/TNFRSF9/CD137 Antibody (OTI5H5) - Azide and BSA Free [NBP2-71035] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TNFRSF9.Applications for 4-1BB/TNFRSF9/CD137 Antibody (OTI5H5) - Azide and BSA Free
Application
Recommended Usage
Western Blot
1:2000
Formulation, Preparation, and Storage
Purification
Immunogen affinity purified
Reconstitution
we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process.
Formulation
Lyophilized from PBS (pH 7.3) with 8% Trehalose
Format
Azide and BSA Free
Preservative
No Preservative
Concentration
LYOPH mg/ml
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at -20C. Avoid freeze-thaw cycles.
Background: 4-1BB/TNFRSF9/CD137
References
1. Etxeberria, I., Glez-Vaz, J., Teijeira, A., & Melero, I. (2020). New emerging targets in cancer immunotherapy: CD137/4-1BB costimulatory axis. ESMO open, 4(Suppl 3), e000733. https://doi.org/10.1136/esmoopen-2020-000733
2. Chester, C., Sanmamed, M. F., Wang, J., & Melero, I. (2018). Immunotherapy targeting 4-1BB: mechanistic rationale, clinical results, and future strategies. Blood, 131(1), 49-57. https://doi.org/10.1182/blood-2017-06-741041
3. Uniport (Q07011)
4. Chester, C., Ambulkar, S., & Kohrt, H. E. (2016). 4-1BB agonism: adding the accelerator to cancer immunotherapy. Cancer Immunology, Immunotherapy: CII, 65(10), 1243-1248. https://doi.org/10.1007/s00262-016-1829-2
5. Zapata, J. M., Perez-Chacon, G., Carr-Baena, P., Martinez-Forero, I., Azpilikueta, A., Otano, I., & Melero, I. (2018). CD137 (4-1BB) signalosome: complexity is a matter of TRAFs. Frontiers in Immunology, 9, 2618. https://doi.org/10.3389/fimmu.2018.02618
Alternate Names
41BB, CD137, ILA, TNFRSF9
Gene Symbol
TNFRSF9
Additional 4-1BB/TNFRSF9/CD137 Products
Product Documents for 4-1BB/TNFRSF9/CD137 Antibody (OTI5H5) - Azide and BSA Free
Product Specific Notices for 4-1BB/TNFRSF9/CD137 Antibody (OTI5H5) - Azide and BSA Free
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Loading...
Loading...
Loading...
Loading...
Loading...