5-HT2C Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-12279

Novus Biologicals, part of Bio-Techne
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NBP3-12279
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Key Product Details

Species Reactivity

Human, Mouse, Rat, Primate

Applications

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all 5-HT2C Antibodies »

Product Specifications

Immunogen

Synthetic peptide taken within amino acid region 400-458 on human 5-hydroxytryptamine receptor 2C.

Reactivity Notes

Baboon (100%).

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for 5-HT2C Antibody

Immunohistochemistry-Paraffin: 5-HT2C Antibody [NBP3-12279]

Immunohistochemistry-Paraffin: 5-HT2C Antibody [NBP3-12279]

Immunohistochemistry-Paraffin: 5-HT2C Antibody [NBP3-12279] - Baboon brain. 1:50 dilution in IHC blocking buffer. DAB (brown) staining and Hematoxylin QS (blue) counterstain. 40X magnification.
Immunohistochemistry-Paraffin: 5-HT2C Antibody [NBP3-12279]

Immunohistochemistry-Paraffin: 5-HT2C Antibody [NBP3-12279]

Immunohistochemistry-Paraffin: 5-HT2C Antibody [NBP3-12279] - Human Fibroepithelial polyp. 1:50 dilution in IHC blocking buffer. DAB (brown) staining and Hematoxylin QS (blue) counterstain. 40X magnification.

Applications for 5-HT2C Antibody

Application
Recommended Usage

ELISA

1:50000

Immunohistochemistry

1:50-1:100

Immunohistochemistry-Paraffin

1:50-1:100

Immunoprecipitation

1:200

Western Blot

1:500

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

Contains Tris, HCl/glycine buffer (pH 7.4-7.8), 30% glycerol, 0.5% BSA, along with cryo-protective agents, and HEPES (exact storage and stabilization buffer information is proprietary).

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Store at -20C long term. Avoid freeze-thaw cycles.

Background: 5-HT2C

Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine neurotransmitter synthesised in serotonergic neurons in the central nervous system and enterochromaffin cells in the gastrointestinal tract. Serotonin plays an important part in the biochemistry of depression, migraine, bipolar disorder and anxiety. It is also believed to be influential on sexuality and appetite. 5-HT is generally thought not to be released from synaptic terminal buttons in the manner of classical neurotransmission but from serotonergic varacosities into the extra neuronal space. From here it is free to diffuse over a relatively large region of space (>20um) and activate 5-HT receptors located on the dendrites, cell bodies and presynaptic terminals of adjacent neurons. Serotonergic action is terminated primarily via uptake of 5-HT from the synapse. This is through the specific monoamine transporter for 5-HT, 5-HT reuptake transporter, on the presynaptic neuron. The pharmacology of 5-HT is extremely complex, with its actions being mediated by a large and diverse range of 5-HT receptors.

Long Name

5-Hydroxytryptamine Receptor 2C

Alternate Names

5-HTR2C, 5HT2C, HTR2C, Serotonin Receptor 2C

Gene Symbol

HTR2C

Additional 5-HT2C Products

Product Documents for 5-HT2C Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for 5-HT2C Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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