53BP2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-90324

Novus Biologicals, part of Bio-Techne
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NBP1-90324
NBP1-90324-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (91%), Rat (90%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all 53BP2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: PQPSKDTLLPPFRKPQTVAASSIYSMYTQQQAPGKNFQQAVQSALTKTHTRGPHFSSVYGKPVIAAAQNQQQHPENIYSNSQGKPGSPEPETEPVSSVQENHENERI

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for 53BP2 Antibody

Immunocytochemistry/ Immunofluorescence: 53BP2 Antibody [NBP1-90324]

Immunocytochemistry/ Immunofluorescence: 53BP2 Antibody [NBP1-90324]

Immunocytochemistry/Immunofluorescence: 53BP2 Antibody [NBP1-90324] - Staining of human cell line A-431 shows localization to cytosol & cell junctions.
Immunohistochemistry: 53BP2 Antibody [NBP1-90324]

Immunohistochemistry: 53BP2 Antibody [NBP1-90324]

Immunohistochemistry: 53BP2 Antibody [NBP1-90324] - Staining of human testis shows strong nuclear positivity in cells of the seminiferus ducts.

Applications for 53BP2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: 53BP2

53BP2 encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternate Names

apoptosis-stimulating protein of p53, 2, ASPP2P53BP2,53BP2apoptosis-stimulating of p53 protein 2, Bbp, Bcl2-binding protein, p53-binding protein 2, p53BP2, PPP1R13A, Renal carcinoma antigen NY-REN-51, tumor protein p53 binding protein, 2, tumor protein p53-binding protein, 2, Tumor suppressor p53-binding protein 2

Gene Symbol

TP53BP2

Additional 53BP2 Products

Product Documents for 53BP2 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for 53BP2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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