A2BP1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-90304

Novus Biologicals, part of Bio-Techne
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NBP1-90304
NBP1-90304-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (96%), Rat (96%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all A2BP1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: PAEYTAPHPHPAPEYTGQTTVPEHTLNLYPPAQTHSEQSPADTSAQTVSGTATQTDDAAPTDGQPQTQPSE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for A2BP1 Antibody

Immunocytochemistry/ Immunofluorescence: A2BP1 Antibody [NBP1-90304]

Immunocytochemistry/ Immunofluorescence: A2BP1 Antibody [NBP1-90304]

Immunocytochemistry/Immunofluorescence: A2BP1 Antibody [NBP1-90304] - Immunofluorescent staining of human cell line U-2 OS shows localization to nucleus & cytosol.
Immunohistochemistry-Paraffin: A2BP1 Antibody [NBP1-90304]

Immunohistochemistry-Paraffin: A2BP1 Antibody [NBP1-90304]

Immunohistochemistry-Paraffin: A2BP1 Antibody [NBP1-90304] - Staining in human cerebral cortex and pancreas tissues using anti-RBFOX1 antibody. Corresponding RBFOX1 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: A2BP1 Antibody [NBP1-90304]

Immunohistochemistry-Paraffin: A2BP1 Antibody [NBP1-90304]

Immunohistochemistry-Paraffin: A2BP1 Antibody [NBP1-90304] - Staining of human cerebral cortex shows moderate nuclear positivity in neuronal cells.
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Applications for A2BP1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: A2BP1

Ataxin-2 binding protein 1 has an RNP motif that is highly conserved among RNA-binding proteins. This protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the gene product of the SCA2 gene which causes familial neurodegenerative diseases. Ataxin-2 binding protein 1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been found but their full length nature has not been determined. (provided by RefSeq)

Alternate Names

2BP1, A2BP, A2BP1 Hexaribonucleotide-binding protein 1, Ataxin-2-binding protein 1, FOX-1, FOX1 hexaribonucleotide binding protein 1, Fox-1 homolog A, HRNBP1 ataxin 2-binding protein 1, RNA binding protein fox-1 homolog 1, RNA binding protein, fox-1 homolog (C. elegans) 1

Gene Symbol

RBFOX1

Additional A2BP1 Products

Product Documents for A2BP1 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for A2BP1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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