AADACL1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-90294

Novus Biologicals, part of Bio-Techne
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NBP1-90294
NBP1-90294-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all AADACL1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: ALIYPVLQALDFNTPSYQQNVNTPILPRYVMVKYWVDYFKGNYDFVQAMIVNNHTSLDVEEAAAVRARLNWTSLLPASFTKNYKPVVQTTGNARIVQELPQLLDARSAPLIADQAVLQLLPKTYILTCEHDVL

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (83%), Rat (83%). Reactivity reported in scientific literature (PMID: 22354961)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for AADACL1 Antibody

Western Blot: AADACL1 Antibody [NBP1-90294]

Western Blot: AADACL1 Antibody [NBP1-90294]

Western Blot: AADACL1 Antibody [NBP1-90294] - Analysis in human cell line CAPAN-2.
Immunocytochemistry/ Immunofluorescence: AADACL1 Antibody [NBP1-90294]

Immunocytochemistry/ Immunofluorescence: AADACL1 Antibody [NBP1-90294]

Immunocytochemistry/Immunofluorescence: AADACL1 Antibody [NBP1-90294] - Staining of human cell line.
Immunohistochemistry-Paraffin: AADACL1 Antibody [NBP1-90294]

Immunohistochemistry-Paraffin: AADACL1 Antibody [NBP1-90294]

Immunohistochemistry-Paraffin: AADACL1 Antibody [NBP1-90294] - Staining of human hippocampus shows strong cytoplasmic positivity in neuronal cells.

Applications for AADACL1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: AADACL1

Hydrolyzes 2-acetyl monoalkylglycerol ether, the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor. May be responsible for cholesterol ester hydrolysis in macrophages, thereby contributing to the development of atherosclerosis. Also involved in organ detoxification by hydrolyzing exogenous organophosphorus compounds. May contribute to cancer pathogenesis by promoting tumor cell migration.

Long Name

Neutral cholesterol ester hydrolase 1

Alternate Names

EC 3.1.1.-, EC 3.1.1.71, KIAA1363, NCEH, NCEH1

Gene Symbol

NCEH1

Additional AADACL1 Products

Product Documents for AADACL1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for AADACL1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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