ABCB5 Antibody (CL13618) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-44328

Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
NBP3-44328
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL13618

Format

Azide and BSA Free

Concentration

LYOPH mg/ml

View all ABCB5 Antibodies »

Product Specifications

Immunogen

This antibody was generated using a synthetic peptide of Q2M3G0, with the exact immunogen sequence remaining proprietary.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for ABCB5 Antibody (CL13618) - Azide and BSA Free

ABCB5 Antibody (CL13618) - Azide and BSA Free Immunohistochemistry-Paraffin: ABCB5 Antibody [NBP3-44328]

Immunohistochemistry-Paraffin: ABCB5 Antibody [NBP3-44328]

Staining of human breast shows strong membranous positivity in glandular cells.
ABCB5 Antibody (CL13618) - Azide and BSA Free Immunohistochemistry-Paraffin: ABCB5 Antibody [NBP3-44328]

Immunohistochemistry-Paraffin: ABCB5 Antibody [NBP3-44328]

Analysis in human epididymis and tonsil tissues using NBP3-44328 antibody. Corresponding ABCB5 RNA-seq data are presented for the same tissues.
ABCB5 Antibody (CL13618) - Azide and BSA Free Immunohistochemistry-Paraffin: ABCB5 Antibody [NBP3-44328]

Immunohistochemistry-Paraffin: ABCB5 Antibody [NBP3-44328]

Staining of human epididymis shows strong membranous positivity in glandular cells.
View 4 more images

Applications for ABCB5 Antibody (CL13618) - Azide and BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Reconstitution

Centrifuge the vial of lyophilized antibody at 12,000 x g for 20 seconds. Reconstitute by adding sterile, distilled water to achieve a final antibody concentration of 1mg/ml.

Formulation

Lyophilized in 5% Trehalose.

Format

Azide and BSA Free

Preservative

0.02% Sodium Azide

Concentration

LYOPH mg/ml

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ABCB5

ATP-Binding Cassette proteins comprise a superfamily of transporters with a wide variety of substrates. ABCB5 is a novel member of the human P-glycoprotein family. It functions as a determinant of membrane potential and regulator of cell fusion in physiologic skin progenitor cells. Cell fusion is thought to contribute to tissue differentiation. ABCB5 is predominantly expressed in melanoma cells and is a novel molecular marker for a distinct subset of chemoresistant stem cell phenotype-expressing tumor cells among human epidermal melanocytes. It has been identified as a novel drug transporter in human malignant melanoma. ABCB5 is a rhodamine efflux transporter. This antibody product is intended to be used to confirm cellular localization and expression level of ABCB5.

Long Name

ATP-binding Cassette, Sub-family B (MDR/TAP), Member 5

Alternate Names

ABCB5 P-gp, ABCB5alpha, ABCB5beta, ATP-binding cassette protein, ATP-binding cassette sub-family B member 5, ATP-binding cassette, sub-family B (MDR/TAP), member 5, EC 3.6.3, EC 3.6.3.44, EST422562, P-glycoprotein ABCB5

Gene Symbol

ABCB5

Additional ABCB5 Products

Product Documents for ABCB5 Antibody (CL13618) - Azide and BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for ABCB5 Antibody (CL13618) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.