ATP-binding cassette (ABC) transporter genes are involved in the regulation of the amount of dietary cholesterol retained in the body. ABCG8, expressed at high levels in the liver and intestine, normally cooperates with ABCG5 to limit intestinal absorption and promote biliary excretion of sterols. The mutated form of this transporter can lead to sterol accumulation and atherosclerosis or sitosterolemia, a rare autosomal recessive disorder, characterized by hyperabsorption of sterols and the inability to excrete sterols into bile.

Alternate Names

ATP-binding cassette sub-family G member 8, ATP-binding cassette, sub-family G (WHITE), member 8, ATP-binding cassette, sub-family G (WHITE), member 8 (sterolin 2), GBD4ATP-binding cassette, subfamily G, member 8, MGC142217, sterolin 2, sterolin-2, STSL

Gene Symbol

ABCG8

Additional ABCG8 Products

Product Documents for ABCG8 Antibody [HRP]

Product Datasheets

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COA

SDS

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Product Specific Notices for ABCG8 Antibody [HRP]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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ABCG8 Antibody [HRP]

Novus Biologicals, part of Bio-Techne | Catalog # NB400-110H

Key Product Details

Species Reactivity

Validated:

Applications

Label

Antibody Source

Concentration

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Product Summary for ABCG8 Antibody [HRP]

Immunogen

Reactivity Notes

Localization

Clonality

Host

Isotype

Applications for ABCG8 Antibody [HRP]

Immunohistochemistry (Negative)

Western Blot

Formulation, Preparation, and Storage

Purification

Formulation

Preservative

Concentration

Shipping

Stability & Storage

Background: ABCG8

Alternate Names

Gene Symbol

Additional ABCG8 Products

Product Documents for ABCG8 Antibody [HRP]

Product Datasheets

COA

Certificate of Analysis

SDS

Product Specific Notices for ABCG8 Antibody [HRP]

CONTACT INFORMATION

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