Abeta 40 Antibody (PSH02-82)
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-32077
Recombinant Monoclonal Antibody
Key Product Details
Species Reactivity
Human, Mouse
Applications
Immunohistochemistry, Immunohistochemistry-Paraffin
Label
Unconjugated
Antibody Source
Recombinant Monoclonal Rabbit IgG Clone # PSH02-82
Concentration
1 mg/ml
Product Specifications
Immunogen
Synthetic peptide within Human Abeta 40 peptide. (Uniprot: P05067)
Localization
Cell membrane, Membrane, Perikaryon, Cell projection, growth cone, Membrane, clathrin-coated pit, Early endosome, Cytoplasmic vesicle.
Clonality
Monoclonal
Host
Rabbit
Isotype
IgG
Theoretical MW
4 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Scientific Data Images for Abeta 40 Antibody (PSH02-82)
Immunohistochemistry: Abeta 40 Antibody (PSH02-82) [NBP3-32077]
Immunohistochemistry: Abeta 40 Antibody (PSH02-82) [NBP3-32077] - Immunohistochemical analysis of paraffin-embedded mouse model of Alzheimer's brain tissue with Rabbit anti-Abeta 40 antibody (NBP3-32077) at 1/1,000 dilution.The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 20 minutes. The tissues were blocked in 1% BSA for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary antibody (NBP3-32077) at 1/1,000 dilution for 1 hour at room temperature. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.
Applications for Abeta 40 Antibody (PSH02-82)
Application
Recommended Usage
Immunohistochemistry-Paraffin
1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A purified
Formulation
PBS (pH7.4), 0.1% BSA and 40% Glycerol
Preservative
0.05% Sodium Azide
Concentration
1 mg/ml
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Background: Abeta 40
The Amyloid beta A4 protein (Abeta40) is the more common isoform and is the main components of amyloid plaques. Abeta-40 is produced by cleavage of the Amyloid Precursor Protein (APP) that occurs in the endoplasmic reticulum.
The Amyloid beta proteins function as a cell surface receptor and supports neurite growth, neuronal adhesion and axonogenesis on the surface of neurons. Amyloid betas are also involved in cell mobility functions and transcription regulation via various protein-protein interactions.
Abeta40 antibodies are useful tools for Alzheimer's studies and research on amyloid plaques.
Alternate Names
amyloid beta 40, Beta-amyloid protein 40
Gene Symbol
APP
Additional Abeta 40 Products
Product Documents for Abeta 40 Antibody (PSH02-82)
Product Specific Notices for Abeta 40 Antibody (PSH02-82)
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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