Activin RIA/ALK-2/Activin Receptor Type 1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-30817

Novus Biologicals, part of Bio-Techne
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NBP3-30817-250ug
NBP3-30817-50ug
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Key Product Details

Species Reactivity

Chicken

Applications

Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Sheep IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Activin RIA/ALK-2 Antibodies »

Product Specifications

Immunogen

Recombinant protein derived from the extracellular domain of the chicken Activin RIA/ALK-2/Activin Receptor Type 1 protein. Protein shares significant homology with the mouse, rat and human sequences.

Clonality

Polyclonal

Host

Sheep

Isotype

IgG

Scientific Data Images for Activin RIA/ALK-2/Activin Receptor Type 1 Antibody

Activin RIA/ALK-2/Activin Receptor Type 1 Antibody

Western Blot: Activin RIA/ALK-2/Activin Receptor Type 1 Antibody [NBP3-30817] -

Western Blot: Activin RIA/ALK-2/Activin Receptor Type 1 Antibody [NBP3-30817] - Western blot using ALK-2 antibody (cat. no. NBP3-30817) on ALK-2 fusion protein.

Applications for Activin RIA/ALK-2/Activin Receptor Type 1 Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

: 5-10 ug/ml

Immunoprecipitation

: 5 ug/mg of protein lysate

Western Blot

: 5-10 ug/ml
Application Notes
.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Ammonium sulfate precipitation

Formulation

Phosphate buffered saline

Preservative

0.08% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Activin RIA/ALK-2

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive.

Long Name

Activin Receptor IA

Alternate Names

ActivinRIA, ACVR1, ALK-2, ALK2

Gene Symbol

ACVR1

Additional Activin RIA/ALK-2 Products

Product Documents for Activin RIA/ALK-2/Activin Receptor Type 1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Activin RIA/ALK-2/Activin Receptor Type 1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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