Activin RIIB Antibody (6L11) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-36066

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 6L11

Format

Azide and BSA Free

Concentration

LYOPH mg/ml

View all Activin RIIB Antibodies »

Product Summary for Activin RIIB Antibody (6L11) - Azide and BSA Free

Immunogen

recombinant human Activin receptor IIB extracellular domain

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for Activin RIIB Antibody (6L11) - Azide and BSA Free

Application
Recommended Usage

Immunohistochemistry

1:10 - 1:500

Immunohistochemistry-Paraffin

1:10-1:500

Western Blot

1:100 - 1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Reconstitution

Centrifuge vial prior to opening. Reconstitute the antibody with 500 ul sterile PBS and the final concentration is 200 ug/ml.

Formulation

PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Activin RIIB

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. This gene encodes activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor. [provided by RefSeq]

Long Name

Activin Receptor IIB

Alternate Names

ActivinRIIB, ACVR2B

Gene Symbol

ACVR2B

Additional Activin RIIB Products

Product Documents for Activin RIIB Antibody (6L11) - Azide and BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Activin RIIB Antibody (6L11) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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