Activin RIIB Antibody (MM0059-6L11) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-12013

Novus Biologicals, part of Bio-Techne
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NBP2-12013
NBP2-12013-0.025mg
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # MM0059-6L11

Format

Azide and BSA Free

Concentration

LYOPH mg/ml

View all Activin RIIB Antibodies »

Product Summary for Activin RIIB Antibody (MM0059-6L11) - Azide and BSA Free

Immunogen

Human recombinant Activin RIIB (extracellular domain)

Specificity

Detects human Activin RIIB. Weak cross-reactivity was found to human Activin RIIA

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Activin RIIB Antibody (MM0059-6L11) - Azide and BSA Free

Immunohistochemistry-Paraffin: Activin RIIB Antibody (MM0059-6L11) - Azide and BSA Free [NBP2-12013]

Immunohistochemistry-Paraffin: Activin RIIB Antibody (MM0059-6L11) - Azide and BSA Free [NBP2-12013]

Immunohistochemistry-Paraffin: Activin RIIB Antibody (MM0059-6L11) [NBP2-12013] - Human placenta (formalin fixed and paraffin embedded) section is subjected to IHC using MM0059-6L11

Applications for Activin RIIB Antibody (MM0059-6L11) - Azide and BSA Free

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:50-1:200

Western Blot

1:100-1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Reconstitution

Reconstitute with sterilized PBS to a final concentration of 0.2 mg/ml.

Formulation

Lyophilized from a 0.2 um filtered solution in PBS. 0.025 mg size is provided in liquid form, PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Activin RIIB

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. This gene encodes activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor. [provided by RefSeq]

Long Name

Activin Receptor IIB

Alternate Names

ActivinRIIB, ACVR2B

Gene Symbol

ACVR2B

UniProt

CAA54671

Additional Activin RIIB Products

Product Documents for Activin RIIB Antibody (MM0059-6L11) - Azide and BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Activin RIIB Antibody (MM0059-6L11) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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