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ACTR1A Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-15274

Novus Biologicals, part of Bio-Techne
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NBP2-15274

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Predicted:

Rhesus Macaque (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human ACTR1A. The exact sequence is proprietary.

Localization

Cytoplasm; cytoskeleton; Centrosome

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

43 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for ACTR1A Antibody

Western Blot: ACTR1A Antibody [NBP2-15274]

Western Blot: ACTR1A Antibody [NBP2-15274]

Western Blot: ACTR1A Antibody [NBP2-15274] - Sample (30 ug of whole cell lysate) A: 293T 10% SDS PAGE, antibody diluted at 1:2000.
Immunohistochemistry-Paraffin: ACTR1A Antibody [NBP2-15274]

Immunohistochemistry-Paraffin: ACTR1A Antibody [NBP2-15274]

Immunohistochemistry-Paraffin: ACTR1A Antibody [NBP2-15274] - Paraffin-embedded Lung ca, using antibody at 1:500 dilution.
Western Blot: ACTR1A Antibody [NBP2-15274]

Western Blot: ACTR1A Antibody [NBP2-15274]

Western Blot: ACTR1A Antibody [NBP2-15274] - Sample (50 ug of whole cell lysate) A: mouse liver 10% SDS PAGE; antibody diluted at 1:1000.

Applications for ACTR1A Antibody

Application
Recommended Usage

Immunohistochemistry

10 - 1:500

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: ACTR1A

This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin. [provided by RefSeq]

Alternate Names

Actin-RPV, alpha-centractin, ARP1 (actin-related protein 1, yeast) homolog A (centractin alpha), ARP1 actin-related protein 1 homolog A, centractin alpha (yeast), ARP1actin-RPV, centractin, Centrosome-associated actin homolog, CTRN1, FLJ52695, FLJ52800, FLJ55002

Gene Symbol

ACTR1A

UniProt

Additional ACTR1A Products

Product Documents for ACTR1A Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for ACTR1A Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.