Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

1.0 mg/ml

View all ADAMTS13 Antibodies »

Product Specifications

Immunogen

A synthetic peptide which maps to a region between residues 250 and 350 of human A Disintegrin-like and Metalloprotease (reprolysin type) with Thrombospondin type 1 motif, 13 using the numbering given in entry XP_088414.1 (GeneID 11093).

Specificity

NB100-584 is specific for human ADAM TS13 protein.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for ADAMTS13 Antibody

Western Blot: ADAMTS13 Antibody [NB100-584]

Western Blot: ADAMTS13 Antibody [NB100-584]

Western Blot: ADAMTS13 Antibody [NB100-584] - Purified recombinant Adam-TS13. Antibody used at the indicated concentrations.

Applications for ADAMTS13 Antibody

Application
Recommended Usage

Western Blot

1:100-1:1000
Application Notes
NB 100-584 has been shown to react with purified recombinant ADAM-TS13 in Western Blot. It has not been tested for reactivity with ADAM-TS13 from native sources, and the antibody is not warranted to have such activity. The suggested WB dilution is for recombinant protein.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: ADAMTS13

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene is the von Willebrand Factor (vWF)-cleaving protease, which is responsible for cleaving at the site of Tyr842-Met843 of the vWF molecule. A deficiency of this enzyme is associated with thrombotic thrombocytopenic purpura. Alternative splicing of this gene generates at least four transcript variants encoding different isoforms.

Long Name

A Disintegrin-like and Metalloproteinase Domain with Thrombospondin Motifs 13

Alternate Names

TTP, vWF-CP

Entrez Gene IDs

11093 (Human)

Gene Symbol

ADAMTS13

Additional ADAMTS13 Products

Product Documents for ADAMTS13 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for ADAMTS13 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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