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Adenosine A2b R Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-44332

Novus Biologicals, part of Bio-Techne
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NBP1-44332

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Monkey (94%), Primate (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

Product Specifications

Immunogen

Synthetic 16 amino acid peptide from internal region of human Adenosine A2b R.

Epitope

Internal region

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (94%), Rabbit (88%), Canine (81%).

Localization

Cell membrane; Multi-pass membrane protein.

Specificity

Human Adenosine A2b R. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for Adenosine A2b R Antibody - BSA Free

Immunohistochemistry-Paraffin: Adenosine A2b R Antibody - BSA Free [NBP1-44332]

Immunohistochemistry-Paraffin: Adenosine A2b R Antibody - BSA Free [NBP1-44332]

Immunohistochemistry-Paraffin: Adenosine A2b R Antibody [NBP1-44332] - Human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Immunohistochemistry-Paraffin: Adenosine A2b R Antibody - BSA Free [NBP1-44332]

Immunohistochemistry-Paraffin: Adenosine A2b R Antibody - BSA Free [NBP1-44332]

Immunohistochemistry-Paraffin: Adenosine A2b R Antibody [NBP1-44332] - Analysis of anti-Adenosine A2b Receptor antibody with human brain, cortex.

Applications for Adenosine A2b R Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

10 ug/ml
Application Notes
IHC: NBP1-44332 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after proteinase K antigen retrieval. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity..

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: Adenosine A2b R

Adenosine is involved in a variety of processes, including the synthesis of urea, the anti-inflammatory response, and the inhibition of protein synthesis. The adenosine receptors, including adenosine A1-R, adenosine A2A-R, adenosine A2B-R, and adenosine A3-R, are integral membrane proteins that are members of the G protein-coupled receptor family. The A1-R protein mediates ureagenesis in a partially calcium-dependent manner. Adenosine is known to mediate coronary vasodilation via the A2A-R receptor. Collagen synthasis and total protein synthesis are inhibited in certain cells by adenosine, acting via the A2B receptors. Activation of the A3-R receptor inhibits the induction of the cytokine TNFalpha and blocks the endotoxin CD14 receptor signal transduction pathway.

Long Name

Adenosine A2b Receptor

Alternate Names

Adenosine A2bR, ADORA2B

Entrez Gene IDs

136 (Human)

Gene Symbol

ADORA2B

UniProt

Additional Adenosine A2b R Products

Product Documents for Adenosine A2b R Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Adenosine A2b R Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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