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Adenylate Cyclase 8 Antibody (ADCY8/7573) [CoraFluor™ 1]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-24065CL1

Novus Biologicals, part of Bio-Techne
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NBP3-24065CL1

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry-Paraffin

Label

CoraFluor 1

Antibody Source

Monoclonal Mouse IgG2 kappa Clone # ADCY8/7573

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for Adenylate Cyclase 8 Antibody (ADCY8/7573) [CoraFluor™ 1]

Immunogen

Recombinant fragment (around aa1-200) of human Adenylate Cyclase 8 protein (exact sequence is proprietary)

Localization

Cell surface. Multi-pass membrane protein. Cytoplasm.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2 kappa

Description

CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.

Applications for Adenylate Cyclase 8 Antibody (ADCY8/7573) [CoraFluor™ 1]

Application
Recommended Usage

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark. Do not freeze.

Background: Adenylate Cyclase 8

ADCY8, also known as Adenylate cyclase type 8, is a 140 kDa 1,251 amino acid protein, and is involved in the encoding of a membrane-bound enzyme that has to do with learning. This protein has also been shown to have interactions with CALM1, CALM2, CALM3, PPP2CA, and CFTR in the Signaling by FGFR, PKA activation in glucagon signaling, DAG and IP3 signaling, Regulation of Water Balance by Renal Aquaporins, and Opioid Signalling pathway. Disease research is currently being studied with relation to ADCY8 and drug dependence, bipolar disorder, cholera, and Alzheimer's disease.

Long Name

Adenylate cyclase type 8

Alternate Names

AC8, ADCY8, Adenylyl cyclase 8

Gene Symbol

ADCY8

Additional Adenylate Cyclase 8 Products

Product Documents for Adenylate Cyclase 8 Antibody (ADCY8/7573) [CoraFluor™ 1]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Adenylate Cyclase 8 Antibody (ADCY8/7573) [CoraFluor™ 1]

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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