Adenylosuccinate Lyase Antibody (16C10) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-59414

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

ELISA, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 16C10

Format

BSA Free

Concentration

1 mg/ml

View all Adenylosuccinate Lyase Antibodies »

Product Specifications

Immunogen

Recombinant human Adenylosuccinate Lyase (1-484aa) purified from E. coli

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for Adenylosuccinate Lyase Antibody (16C10) - BSA Free

Western Blot: Adenylosuccinate Lyase Antibody (16C10)BSA Free [NBP2-59414]

Western Blot: Adenylosuccinate Lyase Antibody (16C10)BSA Free [NBP2-59414]

Western Blot: Adenylosuccinate Lyase Antibody (16C10) [NBP2-59414] - Lane 1: Recombinant Protein, Lane 2: HeLa cell lysates, Lane 3: 293T cell lysates Lane 4: Jurkat cell lysates, Lane 5: HepG2 cell lysates Lane 6: A549 cell lysates Lane 7: MCF7 cell lysates
Immunocytochemistry/ Immunofluorescence: Adenylosuccinate Lyase Antibody (16C10) - BSA Free [NBP2-59414]

Immunocytochemistry/ Immunofluorescence: Adenylosuccinate Lyase Antibody (16C10) - BSA Free [NBP2-59414]

Immunocytochemistry/Immunofluorescence: Adenylosuccinate Lyase Antibody (16C10) [NBP2-59414] - Analysis of ADSL in Hep3B cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human ADSL antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).
Flow Cytometry: Adenylosuccinate Lyase Antibody (16C10) - BSA Free [NBP2-59414]

Flow Cytometry: Adenylosuccinate Lyase Antibody (16C10) - BSA Free [NBP2-59414]

Flow Cytometry: Adenylosuccinate Lyase Antibody (16C10) [NBP2-59414] - Analysis of ADSL in Hep3B cell line, staining at 2-5ug for 1x106cells (red line). The secondary antibody used goat anti-mouse IgG Alexa fluor 488 conjugate. Isotypecontrol antibody was mouse IgG (black line).

Applications for Adenylosuccinate Lyase Antibody (16C10) - BSA Free

Application
Recommended Usage

Flow Cytometry

1:10-1:1024

Immunocytochemistry/ Immunofluorescence

1:100

Western Blot

1:1000

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4), 10% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Adenylosuccinate Lyase

Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Alternate Names

Adenylosuccinase, adenylosuccinate lyase, AMPS, ASase, ASL, EC 4.3.2, EC 4.3.2.2

Gene Symbol

ADSL

Additional Adenylosuccinate Lyase Products

Product Documents for Adenylosuccinate Lyase Antibody (16C10) - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Adenylosuccinate Lyase Antibody (16C10) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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