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Adenylosuccinate Lyase Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-15296

Novus Biologicals, part of Bio-Techne
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NBP2-15296

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Predicted:

Bovine (95%), Chicken (91%), Porcine (97%), Primate (98%), Rat (95%), Xenopus (90%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for Adenylosuccinate Lyase Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human Adenylosuccinate Lyase. The exact sequence is proprietary.

Reactivity Notes

Chimpanzee (98%), Xenopus laevis (90%), Zebrafish (84%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

55 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Adenylosuccinate Lyase Antibody

Western Blot: Adenylosuccinate Lyase Antibody [NBP2-15296]

Western Blot: Adenylosuccinate Lyase Antibody [NBP2-15296]

Western Blot: Adenylosuccinate Lyase Antibody [NBP2-15296] - Sample (30 ug of whole cell lysate) A: Hep G2 10% SDS PAGE ASL antibody, antibody diluted at 1:1000.
Immunohistochemistry-Paraffin: Adenylosuccinate Lyase Antibody [NBP2-15296]

Immunohistochemistry-Paraffin: Adenylosuccinate Lyase Antibody [NBP2-15296]

Immunohistochemistry-Paraffin: Adenylosuccinate Lyase Antibody [NBP2-15296] - Paraffin-embedded mouse fore brain. ADSL antibody [N3C3] dilution: 1:500.

Applications for Adenylosuccinate Lyase Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Adenylosuccinate Lyase

Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Alternate Names

Adenylosuccinase, adenylosuccinate lyase, AMPS, ASase, ASL, EC 4.3.2, EC 4.3.2.2

Gene Symbol

ADSL

UniProt

Additional Adenylosuccinate Lyase Products

Product Documents for Adenylosuccinate Lyase Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Adenylosuccinate Lyase Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.