ADK Antibody (S05-0G0)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-19831

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S05-0G0

Concentration

0.3 mg/ml

View all ADK Antibodies »

Product Summary for ADK Antibody (S05-0G0)

Immunogen

Recombinant protein of human ADK (Uniprot # P55263)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

41 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for ADK Antibody (S05-0G0)

Western Blot: ADK Antibody (S05-0G0) [NBP3-19831]

Western Blot: ADK Antibody (S05-0G0) [NBP3-19831]

Western Blot: ADK Antibody (S05-0G0) [NBP3-19831] - Western blot detection of ADK in Hela, A549, HL-60, U251, U87-MG cell lysates using NBP3-19831 (1:1000 diluted). Predicted band size: 41kDa. Observed band size: 41kDa.
Immunohistochemistry-Paraffin: ADK Antibody (S05-0G0) [NBP3-19831]

Immunohistochemistry-Paraffin: ADK Antibody (S05-0G0) [NBP3-19831]

Immunohistochemistry-Paraffin: ADK Antibody (S05-0G0) [NBP3-19831] - Immunohistochemistry of ADK in paraffin-embedded Human tonsil using NBP3-19831 at dilution 1/50

Applications for ADK Antibody (S05-0G0)

Application
Recommended Usage

Immunohistochemistry

1/100

Western Blot

1/1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ADK

Adenosine kinase (ATP:adenosine 5 prime phosphotransferase) is an abundant enzyme in mammalian tissues that catalyzes the transfer of the gamma phosphate from ATP to adenosine, thereby serving as a potentially important regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of ADK could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as antiinflammatory agents. The encoded protein does not present any sequence similarities to other well characterized mammalian nucleoside kinases. In contrast, 2 regions were identified with significant sequence identity to microbial ribokinase and fructokinases and a bacterial inosine/guanosine kinase. Thus, ADK is a structurally distinct mammalian nucleoside kinase that appears to be akin to sugar kinases of microbial origin.

Long Name

Adenosine Kinase

Alternate Names

AK

Gene Symbol

ADK

Additional ADK Products

Product Documents for ADK Antibody (S05-0G0)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for ADK Antibody (S05-0G0)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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