Adrenomedullin/ADM Antibody (OTI8A1)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-46497

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # OTI8A1

Concentration

1 mg/ml

View all Adrenomedullin/ADM Antibodies »

Product Summary for Adrenomedullin/ADM Antibody (OTI8A1)

Immunogen

Human recombinant protein fragment corresponding to amino acids 22-146 of human ADM(NP_001115) produced in E.coli.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Theoretical MW

20.2 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Adrenomedullin/ADM Antibody (OTI8A1)

Immunohistochemistry: Adrenomedullin/ADM Antibody (OTI8A1) [NBP2-46497]

Immunohistochemistry: Adrenomedullin/ADM Antibody (OTI8A1) [NBP2-46497]

Immunohistochemistry: Adrenomedullin/ADM Antibody (8A1) [NBP2-46497] - Analysis of Human Kidney tissue. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min)

Applications for Adrenomedullin/ADM Antibody (OTI8A1)

Application
Recommended Usage

Immunohistochemistry

1:250
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Adrenomedullin/ADM

Adrenomedullin is a member of the calcitonin family of peptides and functions as a vasodilator. Adrenomedullin, a hypotensive peptide, consists of 52 amino acids, has 1 intramolecular disulfide bond, and shows a slight homology with the calcitonin gene related peptide. Human adrenomedullin mRNA was found to be highly expressed in several tissues. Adrenomedullain is secreted from a number of tissues including the adrenal medulla, endothelial and vascular smooth muscle cells. It has been implicated in a number of diseases including cardiovascular and renal disorders, sepsis, inflammation, diabetes and cancer.

Alternate Names

ADM

Gene Symbol

ADM

Additional Adrenomedullin/ADM Products

Product Documents for Adrenomedullin/ADM Antibody (OTI8A1)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Adrenomedullin/ADM Antibody (OTI8A1)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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