AGTR-1 Antibody (4A9)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-15206

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-15206
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 4A9

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all AGTR-1 Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human AGTR-1. UniProt ID (P30556).

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for AGTR-1 Antibody (4A9)

Western Blot: AGTR-1 Antibody (4A9) [NBP3-15206]

Western Blot: AGTR-1 Antibody (4A9) [NBP3-15206]

Western Blot: AGTR-1 Antibody (4A9) [NBP3-15206] - Positive WB detected in: Hela whole cell lysate, Raji whole cell lysate, MCF-7 whole cell lysate. All lanes: AGTR-1 antibody at 1:2000. Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 42 KDa. Observed band size: 42 KDa.

Applications for AGTR-1 Antibody (4A9)

Application
Recommended Usage

Western Blot

1:500-1:5000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.4), 150mM NaCl, and 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20 to -80C. Avoid freeze-thaw cycles.

Background: AGTR-1

Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. At least four transcript variants have been described for this gene. Additional variants have been described but their full-length nature has not been determined. The entire coding sequence is contained in the terminal exon and is present in all transcript variants.

Long Name

Angiotensin II Receptor Type 1

Alternate Names

AG2S, AGTR1, AT1, AT1AR, AT1BR, AT1R, AT2R1

Gene Symbol

AGTR1

Additional AGTR-1 Products

Product Documents for AGTR-1 Antibody (4A9)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for AGTR-1 Antibody (4A9)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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