AGTR-2 Antibody (6C7)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-26517

Recombinant monoclonal antibody expressed in HEK293F cells
Novus Biologicals, part of Bio-Techne
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NBP3-26517-100ul
NBP3-26517-50ul
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Key Product Details

Species Reactivity

Human, Mouse

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 6C7

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all AGTR-2 Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from Human AGTR-2 [UniProt P50052]

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for AGTR-2 Antibody (6C7)

AGTR-2 Antibody (6C7)

Western Blot: AGTR-2 Antibody (6C7) [NBP3-26517] -

Western Blot: AGTR-2 Antibody (6C7) [NBP3-26517] - Positive Western Blot detected in: 293T whole cell lysate, HepG2 whole cell lysate, A549 whole cell lysate, MCF-7 whole cell lysate, Jurkat whole cell lysate, Mouse liver tissue, Mouse heart tissue.
All lanes: AGTR-2 Antibody at 1: 2000
Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution.
Predicted band size: 42 kDa
Observed band size: 42 kDa

Applications for AGTR-2 Antibody (6C7)

Application
Recommended Usage

Western Blot

1:500-1:5000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl and 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20 to -70C. Avoid freeze-thaw cycles.

Background: AGTR-2

Angiotensin II is a potent pressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors termed AT1 and AT2. AGTR2 belongs to a family 1 of G-protein coupled receptors. It is an intergral membrane protein. It plays a role in the central nervous system and cardiovascular functions that are mediated by the renin-angiotensin system. This receptor mediates programmed cell death (apoptosis). In adults, it is highly expressed in myometrium with lower levels in adrenal gland and fallopian tube. It is highly expressed in fetal kidney and intestine. The human AGTR2 gene is composed of three exons and spans at least 5 kb. Exons 1 and 2 encode for 5; untranslated mRNA sequence and exon 3 harbors the entire uninterrupted open reading frame.

Long Name

Angiostensin II Type 2 Receptor

Alternate Names

AGTR2, AT2, AT2R, MRX88

Gene Symbol

AGTR2

Additional AGTR-2 Products

Product Documents for AGTR-2 Antibody (6C7)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for AGTR-2 Antibody (6C7)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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