AICDA Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-93454

Novus Biologicals, part of Bio-Techne
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NB100-93454
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Cited:

Mouse

Predicted:

Bovine (100%), Porcine (100%). Backed by our 100% Guarantee.

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Peptide ELISA, Western Blot

Cited:

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all AICDA Antibodies »

Product Specifications

Immunogen

Peptide with sequence RRKFLYQFKNVR-C corresponding to N-Terminus according to NP_065712.1.

Reactivity Notes

Use in Mouse reported in scientific literature (PMID:34450044).

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for AICDA Antibody

Western Blot: AICDA Antibody [NB100-93454]

Western Blot: AICDA Antibody [NB100-93454]

Western Blot: AICDA Antibody [NB100-93454] - Staining of Human Tonsil lysate (35ug protein in RIPA buffer). Detected by chemiluminescence.

Applications for AICDA Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:1000

Western Blot

0.1 - 0.3 ug/ml
Application Notes
WB: Approx. 26 kDa band observed in human lymph node, spleen and tonsil lysates (calculated MW of 24.0 kDa band according to NP_065712.1). Use in ICC/IF reported in scientific literature (PMID:34450044).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: AICDA

Activation-induced cytidine deaminase (AID) was initially discovered as a homolog of the apolipoprotein B RNA-editing cytidine deaminase 1 (APOBEC1) that showed cytidine deaminase properties in stimulated B cell lines. It is necessary for somatic hypermutation and class switch recombination in B cells, but inappropriate or dysregulated expression AID is often found in tumors and B cell neoplasms. Although it is structurally and functionally similar to the APOBEC proteins, it appears unlikely that AID deaminates dC to dU residues in HIV cDNA as does APOBEC3G.

Long Name

Activation-Induced Cytidine Deaminase

Alternate Names

AID, Arp2, CDA2, HIGM2

Entrez Gene IDs

57379 (Human)

Gene Symbol

AICDA

UniProt

P00441

Additional AICDA Products

Product Documents for AICDA Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for AICDA Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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