AIPL1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-55506

Novus Biologicals, part of Bio-Techne
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NBP2-55506
NBP2-55506-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all AIPL1 Antibodies »

Product Summary for AIPL1 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: AEVWNEAEAKADLQKVLELEPSMQKAVRRELRLLENRMAEKQEEERLRCRNMLSQGATQPPAEPPTEPPAQSSTEPPAEPPTAPSAELSAGPPAEPATEPPPSPGHSLQH

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for AIPL1 Antibody

Immunocytochemistry/ Immunofluorescence: AIPL1 Antibody [NBP2-55506]

Immunocytochemistry/ Immunofluorescence: AIPL1 Antibody [NBP2-55506]

Immunocytochemistry/Immunofluorescence: AIPL1 Antibody [NBP2-55506] - Staining of human cell line U-2 OS shows localization to nucleoplasm & cytosol.
Immunohistochemistry-Paraffin: AIPL1 Antibody [NBP2-55506]

Immunohistochemistry-Paraffin: AIPL1 Antibody [NBP2-55506]

Immunohistochemistry-Paraffin: AIPL1 Antibody [NBP2-55506] - Staining of human retina shows strong cytoplasmic and nuclear positivity in photoreceptor cells.

Applications for AIPL1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:2500 - 1:5000

Immunohistochemistry-Paraffin

1:2500 - 1:5000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: AIPL1

Leber congenital amaurosis (LCA) accounts for at least 5% of all inherited retinal disease and is the most severe inherited retinopathy with the earliest age of onset. Individuals affected with LCA are diagnosed at birth or in the first few months of life with severely impaired vision or blindness, nystagmus and an abnormal or flat electroretinogram. The photoreceptor/pineal -expressed gene, AIPL1, encoding aryl-hydrocarbon interacting protein-like 1, was mapped within the LCA4 candidate region. The protein contains three tetratricopeptide motifs, consistent with nuclear transport or chaperone activity. AIPL1 mutations may cause approximately 20% of recessive LCA. [provided by RefSeq]

Alternate Names

AIPL2, aryl hydrocarbon receptor interacting protein-like 1, aryl hydrocarbon receptor-interacting protein-like 1, aryl-hydrocarbon-interacting protein-like 1, LCA4

Gene Symbol

AIPL1

Additional AIPL1 Products

Product Documents for AIPL1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for AIPL1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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