AKAP5 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-38713

Novus Biologicals, part of Bio-Techne
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NBP2-38713
NBP2-38713-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all AKAP5 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: LDIQTQTPLNDQATKAKSTQDLSEGISRKDGDEVCESNVSNSITSGEKVISVELGLDNGHSAIQTGTLILEEIE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for AKAP5 Antibody

Immunohistochemistry-Paraffin: AKAP5 Antibody [NBP2-38713]

Immunohistochemistry-Paraffin: AKAP5 Antibody [NBP2-38713]

Immunohistochemistry-Paraffin: AKAP5 Antibody [NBP2-38713] - Staining of human pancreas shows low expression as expected.
Immunohistochemistry: AKAP5 Antibody [NBP2-38713]

Immunohistochemistry: AKAP5 Antibody [NBP2-38713]

Immunohistochemistry: AKAP5 Antibody [NBP2-38713] - Staining of human cerebral cortex shows strong cytoplasmic and nuclear positivity in neuronal cells.
Immunohistochemistry-Paraffin: AKAP5 Antibody [NBP2-38713]

Immunohistochemistry-Paraffin: AKAP5 Antibody [NBP2-38713]

Immunohistochemistry-Paraffin: AKAP5 Antibody [NBP2-38713] - Staining in human cerebral cortex and pancreas tissues using anti-AKAP5 antibody. Corresponding AKAP5 RNA-seq data are presented for the same tissues.

Applications for AKAP5 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: AKAP5

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to the RII-beta regulatory subunit of PKA, and also to protein kinase C and the phosphatase calcineurin. It is predominantly expressed in cerebral cortex and may anchor the PKA protein at postsynaptic densities (PSD) and be involved in the regulation of postsynaptic events. It is also expressed in T lymphocytes and may function to inhibit interleukin-2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT. [provided by RefSeq]

Alternate Names

A kinase (PRKA) anchor protein 5, AKAP 79, AKAP7979kDa, A-kinase anchor protein 79 kDa, A-kinase anchoring protein 75/79, cAMP-dependent protein kinase regulatory subunit II high affinity bindingprotein, cAMP-dependent protein kinase regulatory subunit II high affinity-bindingprotein, H21

Gene Symbol

AKAP5

UniProt

P24588 (Human)

Additional AKAP5 Products

Product Documents for AKAP5 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for AKAP5 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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