ALDH18A1 Antibody (2B5)

Novus Biologicals, part of Bio-Techne | Catalog # H00005832-M01

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

ELISA, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # 2B5

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all ALDH18A1 Antibodies »

Product Specifications

Immunogen

ALDH18A1 (NP_002851, 696 a.a. ~ 795 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. TDVIVTEDENTAEFFLQHVDSACVFWNASTRFSDGYRFGLGAEVGISTSRIHARGPVGLEGLLTTKWLLRGKDHVVSDFSEHGSLKYLHENLPIPQRNTN

Specificity

ALDH18A1 (2B5)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for ALDH18A1 Antibody (2B5)

Western Blot: ALDH18A1 Antibody (2B5) [H00005832-M01]

Western Blot: ALDH18A1 Antibody (2B5) [H00005832-M01]

Western Blot: ALDH18A1 Antibody (2B5) [H00005832-M01] - ALDH18A1 monoclonal antibody (M01), clone 2B5 Analysis of ALDH18A1 expression in MCF-7.
Sandwich ELISA: ALDH18A1 Antibody (2B5) [H00005832-M01] - Detection limit for recombinant GST tagged ALDH18A1 is 0.3 ng/ml as a capture antibody.

Applications for ALDH18A1 Antibody (2B5)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for ELISA.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: ALDH18A1

This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases. Alternatively spliced transcript variants, encoding different isoforms, have been described for this gene.

Alternate Names

aldehyde dehydrogenase 18 family, member A1, Aldehyde dehydrogenase family 18 member A1, delta-1-pyrroline-5-carboxylate synthase, EC 2.1.2.11, EC 2.3.3.13, GSASdelta1-pyrroline-5-carboxlate synthetase, MGC117316, P5CSdelta-1-pyrroline-5-carboxylate synthetase, PYCSEC 1.2.1.41, pyrroline-5-carboxylate synthetase (glutamate gamma-semialdehyde synthetase)

Entrez Gene IDs

5832 (Human)

Gene Symbol

ALDH18A1

OMIM

138250 (Human)

UniProt

NP_002851 (Human)

Additional ALDH18A1 Products

Product Documents for ALDH18A1 Antibody (2B5)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for ALDH18A1 Antibody (2B5)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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