ALDH2 belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. [provided by RefSeq]

Long Name

Aldehyde Dehydrogenase 2 Family Member

Alternate Names

ALDHI, ALDM

Gene Symbol

ALDH2

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Product Documents for ALDH2 Antibody (2C10) [Janelia Fluor® 549]

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Product Specific Notices for ALDH2 Antibody (2C10) [Janelia Fluor® 549]

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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ALDH2 Antibody (2C10) [Janelia Fluor® 549]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-59488JF549

Key Product Details

Species Reactivity

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Product Specifications

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Applications for ALDH2 Antibody (2C10) [Janelia Fluor® 549]

ELISA

Immunocytochemistry/ Immunofluorescence

Western Blot

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Background: ALDH2