Aldo-keto Reductase 1C4/AKR1C4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-40786

Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
NB100-40786
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all Aldo-keto Reductase 1C4/AKR1C4 Antibodies »

Product Specifications

Immunogen

Peptide with sequence DPKYQRVELNDGH-C corresponding to N-Terminus according to NP_001809.2.

Specificity

This antibody may cross-react with AKR1C1

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for Aldo-keto Reductase 1C4/AKR1C4 Antibody

Western Blot: Aldo-keto Reductase 1C4/AKR1C4 Antibody [NB100-40786]

Western Blot: Aldo-keto Reductase 1C4/AKR1C4 Antibody [NB100-40786]

Western Blot: Aldo-keto Reductase 1C4/AKR1C4 Antibody [NB100-40786] - Analysis of Human Liver lysate (35ug protein in RIPA buffer). at 0.1ug/ml.
Immunohistochemistry-Paraffin: Aldo-keto Reductase 1C4/AKR1C4 Antibody [NB100-40786]

Immunohistochemistry-Paraffin: Aldo-keto Reductase 1C4/AKR1C4 Antibody [NB100-40786]

Immunohistochemistry-Paraffin: Aldo-keto Reductase 1C4/AKR1C4 Antibody [NB100-40786] - (2.5ug/ml) staining of paraffin embedded Human Liver. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
Western Blot: Aldo-keto Reductase 1C4/AKR1C4 Antibody [NB100-40786]

Western Blot: Aldo-keto Reductase 1C4/AKR1C4 Antibody [NB100-40786]

Western Blot: Aldo-keto Reductase 1C4/AKR1C4 Antibody [NB100-40786] - (0.1ug/ml) staining of human liver lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for Aldo-keto Reductase 1C4/AKR1C4 Antibody

Application
Recommended Usage

Immunohistochemistry

2 - 4 ug/ml

Immunohistochemistry-Paraffin

2 - 4 ug/ml

Peptide ELISA

Detection limit 1:4000

Western Blot

0.1 - 0.3 ug/ml
Application Notes
WB: Approx. 35 kDa band observed in human liver lysates (calculated MW of 37.1 kDa band according to NP_001809.2). IHC-P: Human liver shows staining of distinct structures in the cytoplasm of hepatocytes.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Aldo-keto Reductase 1C4/AKR1C4

The AKR1A1 gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member, also known as aldehyde reductase, is involved in the reduction of biogenic and xenobiotic aldehydes and is present in virtually every tissue. Alternative splicing of this gene results in two transcript variants encoding the same protein.

Long Name

Aldo-keto Reductase Family 1, Member C4

Alternate Names

3-alpha-HSD, AKR1C4, AldoketoReductase 1C4, CDR, CHDR, DD4, HAKRA

Entrez Gene IDs

1109 (Human)

Gene Symbol

AKR1C4

UniProt

NP_001809.2 (Human)

Additional Aldo-keto Reductase 1C4/AKR1C4 Products

Product Documents for Aldo-keto Reductase 1C4/AKR1C4 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Aldo-keto Reductase 1C4/AKR1C4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.