ALK-1 Antibody (SR2004)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21752

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-21752-100ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR2004

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all ALK-1 Antibodies »

Product Summary for ALK-1 Antibody (SR2004)

Immunogen

A synthesized peptide derived from human ALK-1 (Uniprot #: P37023)

Specificity

Detects endogenous levels of total ALK-1

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

56 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for ALK-1 Antibody (SR2004)

Western Blot: ALK-1 Antibody (SR2004) [NBP3-21752] -

Western Blot: ALK-1 Antibody (SR2004) [NBP3-21752] - Western blot analysis using NBP3-21752 in (1) Jurkat cell lysate; (2) Mouse kidney lysate; (3) Rat kidney lysate.

Applications for ALK-1 Antibody (SR2004)

Application
Recommended Usage

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ALK-1

LTK, ALK and Ros have been identified as receptor tyrosine kinases having sequence similarity to the insulin receptor subfamily of kinases. LTK (leukocyte tyrosine kinase) is expressed in murine B lymphocyte precursors and has also been found in forebrain neurons. ALK (anaplastic lymphoma kinase) is normally highly expressed, specifically in the nervous system. A truncated form containing the catalytic domian of ALK is expressed as the result of a translocation occurring in many non-Hodgkin's lymphomas. The c-Ros gene was originally identified in mutant form as an oncogene. Ros is normally expressed in a small number of epithelial cell types and may play a role in epithelial development.

Long Name

Activin Receptor-like Kinase 1

Alternate Names

ACVRL1, ALK1

Gene Symbol

ACVRL1

Additional ALK-1 Products

Product Documents for ALK-1 Antibody (SR2004)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for ALK-1 Antibody (SR2004)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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