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Alkaline Phosphatase/ALPP Antibody (H17E2)

Novus Biologicals, part of Bio-Techne | Catalog # NB600-750

Novus Biologicals, part of Bio-Techne
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NB600-750
NB600-750-0.025mg

Key Product Details

Species Reactivity

Human

Applications

ELISA, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # H17E2

Concentration

1.0 mg/ml

Product Specifications

Immunogen

Placental membrane

Localization

Attached to the membrane by a GPI-anchor.

Specificity

This recognises human placental alkaline phosphate. The has been widely used in immunolocalisation studies of germ cell tumours and may also be used in ELISA based assays for the measurement of soluble PLAP.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for Alkaline Phosphatase/ALPP Antibody (H17E2)

Application
Recommended Usage

ELISA

1:100-1:2000

Flow Cytometry

10 ug/ml

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Frozen

1:10-1:500
Application Notes
The epitope recognised by this antibody is reported to be sensitive to formaldehyde fixation and tissue processing. The use of acetone fixation for frozen sections is recommended. This antibody does not work in Immunohistochemistry-Paraffin.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Alkaline Phosphatase/ALPP

Alkaline phosphatases are phosphodiesterases. The placental-specific isozyme of Alkaline Phosphatase (PLAP) is found in trophoblast cells of normal human mature placenta, seminomas of testis and ovarian carcinomas. Detection of alkaline phosphatase in serum is a marker for ovarian and testicular cancer.

Long Name

Alkaline Phosphatase, Placental Type

Alternate Names

Alkaline Phosphatase, PLAP, SEAP

Gene Symbol

ALPP

UniProt

Additional Alkaline Phosphatase/ALPP Products

Product Documents for Alkaline Phosphatase/ALPP Antibody (H17E2)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Alkaline Phosphatase/ALPP Antibody (H17E2)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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