alpha 1-Microglobulin Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-62165

Novus Biologicals, part of Bio-Techne
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NB100-62165-0.1ml
NB100-62165
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunodiffusion

Label

Unconjugated

Antibody Source

Polyclonal Sheep IgG

Concentration

5.0 mg/ml

View all alpha 1-Microglobulin Antibodies »

Product Specifications

Immunogen

Highly pure human alpha-1-microglobulin, prepared from the urine of patients with chronic renal proteinuria, molecular weight 25-30 kDa

Reactivity Notes

Does not react with:Rat

Localization

Secreted

Specificity

This antibody recognises human alpha-1-microglobulin. No cross-reactivity is observed with urine albumin, retinol binding protein or beta-2-microglobulin.

Clonality

Polyclonal

Host

Sheep

Isotype

IgG

Scientific Data Images for alpha 1-Microglobulin Antibody

ELISA: alpha 1-Microglobulin Antibody [NB100-62165]

ELISA: alpha 1-Microglobulin Antibody [NB100-62165]

ELISA: alpha 1-Microglobulin Antibody [NB100-62165] - Analysis of HRP conjugate of NB100-62165. Native Human Alpha-1 Microglobulin detected with Sheep anti Human Alpha-1 Microglobulin:HRP

Applications for alpha 1-Microglobulin Antibody

Application
Recommended Usage

ELISA

1:100-1:2000

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Preservative

0.09% Sodium Azide

Concentration

5.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: alpha 1-Microglobulin

Alpha 1-microglobulin (A1M) is an immunomodulatory protein with a broad spectrum of possible clinical applications and seems a promising marker for evaluation of tubular function. Alpha(1)microglobulin/bikunin precursor specifically interacts with the ORF3 protein of hepatitis E virus and has a direct role in enhancing alpha(1)microglobulin export from the hepatocyte. Bikunin has a role in downregulating PI3 kinase and suppressing tumor invasiveness and metastasis in ovaran cancer cells. I-alpha-I plasma protease inhibitors are assembled from one or two heavy chains (H1, H2 or H3) and one light chain, bikunin. Inter-alpha-inhibitor (I-alpha-I) is composed of H1, H2 and bikunin, inter-alpha-like inhibitor (I-alpha-LI) of H2 and bikunin, and pre-alpha-inhibitor (P-alpha-I) of H3 and bikunin. Interacts with FN1

Alternate Names

A1M, alpha 1Microglobulin, AMBP, EDC1, HCP, HI30, IATIL, ITI, ITIL, ITILC, UTI

Entrez Gene IDs

259 (Human)

Gene Symbol

AMBP

UniProt

P02760 (Human)

Additional alpha 1-Microglobulin Products

Product Documents for alpha 1-Microglobulin Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for alpha 1-Microglobulin Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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