alpha-2B Adrenergic R/ADRA2B Antibody (5G10)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-66606

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Mouse, Rat

Applications

Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 5G10

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all alpha-2B Adrenergic R/ADRA2B Antibodies »

Product Specifications

Immunogen

Mouse monoclonal antibody raised to a synthetic peptide corresponding to the third intracellular loop of the rat alpha-2B Adrenergic R/ADRA2B (Uniprot: P19328).

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for alpha-2B Adrenergic R/ADRA2B Antibody (5G10)

Western Blot: alpha-2B Adrenergic R/ADRA2B Antibody (5G10) [NBP2-66606]

Western Blot: alpha-2B Adrenergic R/ADRA2B Antibody (5G10) [NBP2-66606]

Western Blot: alpha-2B Adrenergic R/ADRA2B Antibody (5G10) [NBP2-66606] - alpha2B adrenergic receptor antibody on MDCK cells transfected to produce alpha2B receptor protein.

Applications for alpha-2B Adrenergic R/ADRA2B Antibody (5G10)

Application
Recommended Usage

Western Blot

5-10 ug/ml
Application Notes
.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS

Preservative

0.08% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: alpha-2B Adrenergic R/ADRA2B

The rat alpha 2b adrenergic receptor is a G protein coupled receptor which acts through Gi2 and is responsible for Cellular communication and signal transduction. These receptors are linked to pertussis toxin-sensitive G proteins. Agonist binding leads to inhibition of adenylyl cyclase, inhibition of Ca(2+) channels and activation of K(+) channels. Recently, three distinct subtypes of alpha(2)-AR were described, alpha(2A)-AR, alpha(2B)-AR and alpha(2C)-AR. At present, it is unknown which of these alpha(2)-AR subtype(s) may regulate insulin secretion.

Long Name

Alpha-2B Adrenergic Receptor

Alternate Names

a-2B AdrenergicR, ADRA2B, ADRA2L1, ADRA2RL1, ADRARL1, alpha2B AdrenergicR

Gene Symbol

ADRA2B

UniProt

P19328 (Rat)

Additional alpha-2B Adrenergic R/ADRA2B Products

Product Documents for alpha-2B Adrenergic R/ADRA2B Antibody (5G10)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for alpha-2B Adrenergic R/ADRA2B Antibody (5G10)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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