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alpha-2C Adrenergic R/ADRA2C Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-14537

Novus Biologicals, part of Bio-Techne
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NBP3-14537

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Monkey (100%), Primate (94%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

1 mg/ml

Product Specifications

Immunogen

Synthetic 18 amino acid peptide from 3rd cytoplasmic domain of human alpha-2C Adrenergic R/ADRA2C.

Epitope

Cytoplasmic Domain

Reactivity Notes

Expected reactivity based on percent sequence identity: Mouse, Rat (89%)

Specificity

Human alpha-2C Adrenergic R/ADRA2C. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for alpha-2C Adrenergic R/ADRA2C Antibody

Immunohistochemistry-Paraffin: alpha-2C Adrenergic R/ADRA2C Antibody [NBP3-14537]

Immunohistochemistry-Paraffin: alpha-2C Adrenergic R/ADRA2C Antibody [NBP3-14537]

Immunohistochemistry-Paraffin: alpha-2C Adrenergic R/ADRA2C Antibody [NBP3-14537] - Immunohistochemistry of formalin-fixed, paraffin-embedded human artery, smooth muscle, after heat-induced antigen retrieval.

Applications for alpha-2C Adrenergic R/ADRA2C Antibody

Application
Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

0.1% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: alpha-2C Adrenergic R/ADRA2C

The alpha-2-adrenergic receptor is a member of the G protein-coupled receptor superfamily. There are 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Alpha2C is required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons.

Long Name

Alpha-2C Adrenergic Receptor

Alternate Names

a-2C AdrenergicR, ADRA2C, ADRA2L2, ADRA2RL2, ADRARL2, alpha2C AdrenergicR

Gene Symbol

ADRA2C

Additional alpha-2C Adrenergic R/ADRA2C Products

Product Documents for alpha-2C Adrenergic R/ADRA2C Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for alpha-2C Adrenergic R/ADRA2C Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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