Alpha Actinin 2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-90376

Novus Biologicals, part of Bio-Techne
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NBP1-90376
NBP1-90376-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (97%), Rat (97%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all alpha Actinin 2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: AHEQFKATLPEADGERQSIMAIQNEVEKVIQSYNIRISSSNPYSTVTMDELRTKWDKVKQLVPIRDQSLQEELARQHANERLRRQFAAQANAIGPWIQNKMEEIARSSIQITGALEDQMNQLKQYEHNIINYKNNIDKLEGD

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Alpha Actinin 2 Antibody

Immunohistochemistry-Paraffin: Alpha Actinin 2 Antibody [NBP1-90376]

Immunohistochemistry-Paraffin: Alpha Actinin 2 Antibody [NBP1-90376]

Immunohistochemistry-Paraffin: Alpha Actinin 2 Antibody [NBP1-90376] - Staining of human skeletal muscle shows high expression.
Immunohistochemistry-Paraffin: Alpha Actinin 2 Antibody [NBP1-90376]

Immunohistochemistry-Paraffin: Alpha Actinin 2 Antibody [NBP1-90376]

Immunohistochemistry-Paraffin: Alpha Actinin 2 Antibody [NBP1-90376] - Staining of human prostate shows low expression as expected.
Immunohistochemistry-Paraffin: Alpha Actinin 2 Antibody [NBP1-90376]

Immunohistochemistry-Paraffin: Alpha Actinin 2 Antibody [NBP1-90376]

Immunohistochemistry-Paraffin: Alpha Actinin 2 Antibody [NBP1-90376] - Staining in human skeletal muscle and prostate tissues using anti-ACTN2 antibody. Corresponding ACTN2 RNA-seq data are presented for the same tissues.

Applications for Alpha Actinin 2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: alpha Actinin 2

Alpha actinin 2 is an actin binding proteins that carry out different purposes in different different cell types. Skeletal, cardiac, and smooth muscle isoforms are localized to the Z disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. ACTN2 encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. There are several known transcript variants that result from the use of multiple polyA+ sites. ACTN2 has the ability to form both homo- and heterodimers (with ACTN3).

Long Name

Actinin alpha 2

Alternate Names

Actinin alpha 2, Actinin-a2, ACTN2, alpha-Actinin 2, Alpha-Actinin Skeletal Muscle, Alpha-Actinin-2, CMD1AA

Gene Symbol

ACTN2

Additional alpha Actinin 2 Products

Product Documents for Alpha Actinin 2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Alpha Actinin 2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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