alpha-Galactosidase A/GLA Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-89797

Novus Biologicals, part of Bio-Techne
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NBP1-89797
NBP1-89797-25ul
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Key Product Details

Validated by

Orthogonal Validation, Independent Antibodies

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all alpha-Galactosidase A/GLA Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: FDGCYCDSLENLADGYKHMSLALNRTGRSIVYSCEWPLYMWPFQKPNYTEIRQYCNHWRNFADIDDSWKSIKSILDWTSFNQERIVDVAGPGGWNDPDMLVIGNFGLSWNQQVTQMA

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for alpha-Galactosidase A/GLA Antibody

Immunohistochemistry-Paraffin: alpha-Galactosidase A/GLA Antibody [NBP1-89797]

Immunohistochemistry-Paraffin: alpha-Galactosidase A/GLA Antibody [NBP1-89797]

Immunohistochemistry-Paraffin: alpha-Galactosidase A/GLA Antibody [NBP1-89797] - Staining of human colon.
Immunohistochemistry: alpha-Galactosidase A/GLA Antibody [NBP1-89797]

Immunohistochemistry: alpha-Galactosidase A/GLA Antibody [NBP1-89797]

Immunohistochemistry: alpha-Galactosidase A/GLA Antibody [NBP1-89797] - Staining of human adrenal gland shows strong granular positivity in cytoplasm of cortical cells.
Immunohistochemistry-Paraffin: alpha-Galactosidase A/GLA Antibody [NBP1-89797]

Immunohistochemistry-Paraffin: alpha-Galactosidase A/GLA Antibody [NBP1-89797]

Immunohistochemistry-Paraffin: alpha-Galactosidase A/GLA Antibody [NBP1-89797] - Staining of human pancreas shows low expression as expected.
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Applications for alpha-Galactosidase A/GLA Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: alpha-Galactosidase A/GLA

Galactosidase alpha encodes a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties. [provided by RefSeq]

Alternate Names

Agalsidase alpha, GALA, Melibiase

Gene Symbol

GLA

Additional alpha-Galactosidase A/GLA Products

Product Documents for alpha-Galactosidase A/GLA Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for alpha-Galactosidase A/GLA Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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