alpha-Methylacyl-CoA Racemase/AMACR Antibody (RM349)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-77417

Recombinant Monoclonal Antibody.
Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # RM349

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all alpha-Methylacyl-CoA Racemase/AMACR Antibodies »

Product Specifications

Immunogen

A peptide corresponding to residues in human alpha-Methylacyl-CoA Racemase/AMACR

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for alpha-Methylacyl-CoA Racemase/AMACR Antibody (RM349)

Western Blot: alpha-Methylacyl-CoA Racemase/AMACR Antibody (RM349) [NBP2-77417]

Western Blot: alpha-Methylacyl-CoA Racemase/AMACR Antibody (RM349) [NBP2-77417]

Western Blot: alpha-Methylacyl-CoA Racemase/AMACR Antibody (RM349) [NBP2-77417] - Western Blot of LNCaP cell lysate using NBP2-77417.
Immunohistochemistry: alpha-Methylacyl-CoA Racemase/AMACR Antibody (RM349) [NBP2-77417]

Immunohistochemistry: alpha-Methylacyl-CoA Racemase/AMACR Antibody (RM349) [NBP2-77417]

Immunohistochemistry: alpha-Methylacyl-CoA Racemase/AMACR Antibody (RM349) [NBP2-77417] - Immunohistochemical staining of formalin fixed and paraffin embedded human kidney tissue section using NBP2-77417.

Applications for alpha-Methylacyl-CoA Racemase/AMACR Antibody (RM349)

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Western Blot

1:1000 - 1:2000

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50% Glycerol/PBS, 1% BSA

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: alpha-Methylacyl-CoA Racemase/AMACR

AMACR (alpha-methylacyl-CoA racemase) has been recently described as prostate cancer-specific gene that encodes a protein involved in the beta-oxidation of branched chain fatty acids. Expression of AMACR protein is found in prostatic adenocarcinoma but not in benign prostatic tissue. It stains premalignant lesions of prostate: high-grade prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia. AMACR can be used as a positive marker for PIN. Defects in AMACR are the cause of congenital bile acid synthesis defect type 4 (CBAS4); also known as cholestasis, intrahepatic, with defective conversion of trihydroxycoprostanic acid to cholic acid or trihydroxycoprostanic acid in bile. Clinical features include neonatal jaundice, intrahepatic cholestasis, bile duct deficiency and absence of cholic acid from bile.

Alternate Names

alphaMethylacylCoARacemase, AMACR, AMACRD, CBAS4, RACE

Gene Symbol

AMACR

Additional alpha-Methylacyl-CoA Racemase/AMACR Products

Product Documents for alpha-Methylacyl-CoA Racemase/AMACR Antibody (RM349)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for alpha-Methylacyl-CoA Racemase/AMACR Antibody (RM349)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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