Key Product Details

Species Reactivity

Human, Rat, Bovine

Applications

ELISA, Immunohistochemistry

Label

DyLight 550 (Excitation = 562 nm, Emission = 576 nm)

Antibody Source

Monoclonal Mouse IgG1 Clone # 3A10.C9

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all AlphaB Crystallin/CRYAB Antibodies »

Product Specifications

Immunogen

Native Alpha B Crystallin

Localization

Cytoplasm , Nucleus

Specificity

Detects approx 20kDa (predicted mol.weight is approx 21kDa). Does not cross-react with alpha A-crystallin, Beta L-crystallin, Beta H-crystallin, gamma-crystallin, HSP25, HSP27 or HSP47 proteins.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for AlphaB Crystallin/CRYAB Antibody (3A10.C9) [DyLight 550]

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: AlphaB Crystallin/CRYAB

Crystallin AB is a member of the small heat shock protein family and expressed in several tissues including brain, kidney cardiac and skeletal muscle. Crystallin AB functions as a molecular chaperone and in intracellular architecture. Crystallin AB has shown to have interactions with CRYAA, CRYGC, CRYBB2, CRYBA1 and HSPB8. Defects in crystalline AB have been linked to cause myopathy myofibrillar type 2, cataract posterior polar type 2, and myopathy myofibrillar fatal infantile hypertonic alpha-B crystallin-related (MFMFIH-CRYAB).

Alternate Names

CRYA2, CRYAB, CTPP2, HSPB5

Entrez Gene IDs

1410 (Human)

Gene Symbol

CRYAB

UniProt

NP_001876.1 (Human), P02511 (Human)

Additional AlphaB Crystallin/CRYAB Products

Product Documents for AlphaB Crystallin/CRYAB Antibody (3A10.C9) [DyLight 550]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for AlphaB Crystallin/CRYAB Antibody (3A10.C9) [DyLight 550]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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