ALS2CR2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-24680

Novus Biologicals, part of Bio-Techne
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NBP2-24680
NBP2-24680SS
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Key Product Details

Species Reactivity

Validated:

Human, Bovine, Canine, Equine, Primate

Predicted:

Chicken (94%), Mouse (94%), Opossum (94%), Rat (94%), Zebrafish (90%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all ALS2CR2 Antibodies »

Product Specifications

Immunogen

A portion of amino acids 200-250 of human Als2Cr2 was used as the immunogen for the antibody.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ALS2CR2 Antibody

Western Blot: ALS2CR2 Antibody [NBP2-24680]

Western Blot: ALS2CR2 Antibody [NBP2-24680]

Western Blot: ALS2CR2 Antibody [NBP2-24680] - analysis of Als2Cr2 in human brain lysate in the 1) absence and 2) presence of immunizing peptide, and 3) mouse brain using Als2Cr2 antibody at 4.0 ug/ml and 2 ug/ml, respectively.
Immunohistochemistry-Paraffin: ALS2CR2 Antibody [NBP2-24680]

Immunohistochemistry-Paraffin: ALS2CR2 Antibody [NBP2-24680]

Immunohistochemistry-Paraffin: ALS2CR2 Antibody [NBP2-24680] - Formalin-fixed, paraffin-embedded human kidney stained with Als2Cr2 antibody at 20 ug/ml. Tubule staining can be seen. Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM sodium citrate buffer, pH 6.0 for 10-20 min followed by cooling at RT for 20 min.

Applications for ALS2CR2 Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

5 ug/ml

Western Blot

2.0-4.0 ug/ml

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

0.2 ml PBS and 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: ALS2CR2

ALS2CR2 encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene. [provided by RefSeq]

Alternate Names

ALS2CR2candidate 2, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein, CALS-21MGC102916, ILP-interacting protein, ILPIPSTRAD beta, Pseudokinase ALS2CR2, STE20-related kinase adaptor beta

Gene Symbol

STRADB

UniProt

Q9C0K7 (Human)

Additional ALS2CR2 Products

Product Documents for ALS2CR2 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for ALS2CR2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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