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Amyloid Oligomers Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-97930

Novus Biologicals, part of Bio-Techne
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NBP1-97930-0.025ml
NBP1-97930

Key Product Details

Species Reactivity

Human, Mouse, Rat, Eukaryote

Applications

Validated:

Dot Blot, ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Cited:

Cytometric Bead Assay Standard, Dot Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Synthetic molecular mimic of soluble oligomers

Reactivity Notes

Immunogen displays sequence identity for non-tested species: Eukaryotes.

Localization

Membrane

Specificity

Recognizes all types of amyloid oligomers. Appears to recognize a peptide backbone epitope that is common to amyloid oligomers, but is not found in native proteins, amyloidogenic monomer or mature amyloid fibrils.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Amyloid Oligomers Antibody

Western Blot: Amyloid Oligomers Antibody [NBP1-97930]

Western Blot: Amyloid Oligomers Antibody [NBP1-97930]

Western Blot: Amyloid Oligomers Antibody [NBP1-97930] - Western blot analysis of Human Abeta42 fibrils and prefibrillar oligomers showing detection of Amyloid Oligomers Oligomers (A11) protein using Rabbit Anti-Amyloid Oligomers Oligomers (A11) Polyclonal Antibody (NBP1-97930). Primary Antibody: Rabbit Anti-Amyloid Oligomers Oligomers (A11) Polyclonal Antibody (NBP1-97930) at 1:1000. Courtesy of: Kayed, R., Head, E., Thompson, J. L., McIntire, T. M., Milton, S. C., Cotman, C. W., et al. (2003). Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis. Science 300, 486-489. doi: 10.1126/science.1079469.

Applications for Amyloid Oligomers Antibody

Application
Recommended Usage

ELISA

0.1-10 ug/ml

Immunohistochemistry

1:1000-1:10000

Immunohistochemistry-Paraffin

1:1000-1:10000

Immunoprecipitation

1:1000

Western Blot

1:1000
Application Notes
A 1:1000 dilution of Amyloid Oligomers (A11) Antibody was sufficient for detection of amyloid oligomers in 10 ug of mouse brain lysates by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary Antibody.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, 50% Glycerol

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Amyloid Oligomers

Alternate Names

eukaryotic translation initiation factor 3 subunit p42

Entrez Gene IDs

351 (Human)

Gene Symbol

APP

UniProt

Additional Amyloid Oligomers Products

Product Documents for Amyloid Oligomers Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Amyloid Oligomers Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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