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AP3M1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-27068

Novus Biologicals, part of Bio-Techne
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NBP2-27068
NBP2-27068SS

Key Product Details

Species Reactivity

Validated:

Human, Bovine, Canine, Chicken, Chinese Hamster, Equine

Predicted:

Monkey (100%), Mouse (100%), Opossum (100%), Orangutan (100%), Porcine (100%), Primate (100%), Rabbit (100%), Rat (100%), Rhesus Macaque (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

Product Specifications

Immunogen

The immunogen for this antibody was a portion of amino acid 140-190 of human AP3M1.

Reactivity Notes

The amino acid sequence used as immunogen for the AP3 antibody is 100% homologous in Macaque.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for AP3M1 Antibody

Western Blot: AP3M1 Antibody [NBP2-27068]

Western Blot: AP3M1 Antibody [NBP2-27068]

Western Blot: AP3M1 Antibody [NBP2-27068] - Analysis of human Daudi lysate in the 1) absence and 2) presence of immunizing peptide probed with AP3 antibody at 4 ug/ml.
Immunohistochemistry-Paraffin: AP3M1 Antibody [NBP2-27068]

Immunohistochemistry-Paraffin: AP3M1 Antibody [NBP2-27068]

Immunohistochemistry-Paraffin: AP3M1 Antibody [NBP2-27068] - Formalin-fixed, paraffin-embedded human lung (respiratory epithelium) stained with AP3 antibody at 10 ug/ml.

Applications for AP3M1 Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

10ug/ml

Western Blot

3-5ug/ml~

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

0.2 ml PBS and 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: AP3M1

Adaptor Protein 3 complex subunit mu-1 (AP3M1) belongs to the adaptor complexes medium subunit family and it contains one MHD (mu homology) domain. AP3 is a hetero-tetrameric protein complex composed of four subunits: two large (delta and beta3), one medium (mu3a/M1), and one small (sigma 3). Mutations in one of the large subunits of AP3 have been associated with the Hermansky-Pudlak syndrome, a genetic disorder characterized by defective lysosome-related organelles. It is also reported that AP3, is responsible for the trafficking of TLR9 to recognize viral nucleic acid. AP3 is also involved with a susceptibility gene for schizophrenia, dysbindin.

Alternate Names

adaptor-related protein complex 3, mu 1 subunit, AP-3 adapter complex mu3A subunit, MGC22164, mu-3A subunit, mu3A-adaptin

Gene Symbol

AP3M1

UniProt

Additional AP3M1 Products

Product Documents for AP3M1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for AP3M1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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