AP3M1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-48834

Novus Biologicals, part of Bio-Techne
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NBP2-48834
NBP2-48834-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all AP3M1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: SGDIFLEKHWKSVVSQSVCDYFFEAQ

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for AP3M1 Antibody

Immunohistochemistry: AP3M1 Antibody [NBP2-48834]

Immunohistochemistry: AP3M1 Antibody [NBP2-48834]

Immunohistochemistry: AP3M1 Antibody [NBP2-48834] - Staining of human kidney shows moderate cytoplasmic positivity in cells in tubules.

Applications for AP3M1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: AP3M1

The protein encoded by the AP3M1 gene is the medium subunit of AP-3, which is an adaptor-related protein complex associated with the Golgi region as well as more peripheral intracellular structures. AP-3 facilitates the budding of vesicles from the Golgi membrane and may be directly involved in protein sorting to the endosomal/lysosomal system. AP-3 is a heterotetrameric protein complex composed of two large subunits (delta and beta3), a medium subunit (mu3), and a small subunit (sigma 3). Mutations in one of the large subunits of AP-3 have been associated with the Hermansky-Pudlak syndrome, a genetic disorder characterized by defective lysosome-related organelles. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq]

Alternate Names

adaptor-related protein complex 3, mu 1 subunit, AP-3 adapter complex mu3A subunit, MGC22164, mu-3A subunit, mu3A-adaptin

Gene Symbol

AP3M1

Additional AP3M1 Products

Product Documents for AP3M1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for AP3M1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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