AP4E1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-89056

Novus Biologicals, part of Bio-Techne
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NBP1-89056
NBP1-89056-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (95%), Rat (95%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all AP4E1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: AELNHNVTYAILFECVHTVYSIYPKSELLEKAAKCIGKFVLSPKINLKYLGLKALTYVIQQDPTLALQHQMTIIECLDHPDPIIKRETLELLYRITNAQNITV

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for AP4E1 Antibody

Immunohistochemistry-Paraffin: AP4E1 Antibody [NBP1-89056]

Immunohistochemistry-Paraffin: AP4E1 Antibody [NBP1-89056]

Immunohistochemistry-Paraffin: AP4E1 Antibody [NBP1-89056] - Staining of human small intestine shows strong cytoplasmic positivity in glandular cells.

Applications for AP4E1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: AP4E1

AP4E1, also known as AP-4 complex subunit epsilon-1, contains a 127 kDa and a 119 kDa isoform, and is a part of a clathrin- or nonclathrin-coated vesicle, which pursues proteins from the trans-Golgi network as they move towards the endosomal-lysosomal system. Current research is being conducted to determine the relation between AP4E1 and several diseases and disorders, such as paraplegia, neuronitis, intellectual disability, spasticity, malaria, short stature, and cerebriitis. The protein is linked to intracellular protein transport and Golgi associated vesicle biogenesis, through which it interacts with AP4B1, ARF1, AP4M1, AP4S1, and ALB.

Alternate Names

Adapter-related protein complex 4 subunit epsilon-1, adaptor-related protein complex 4, epsilon 1 subunit, adaptor-related protein complex AP-4 epsilon, AP-4 adapter complex subunit epsilon, AP-4 complex subunit epsilon-1, AP-4-EPSILON, DKFZp686L12167, Epsilon subunit of AP-4, epsilon-adaptin

Entrez Gene IDs

23431 (Human)

Gene Symbol

AP4E1

UniProt

Q9UPM8 (Human)

Additional AP4E1 Products

Product Documents for AP4E1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for AP4E1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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