APBA1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-06015

Novus Biologicals, part of Bio-Techne
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NBP1-06015
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all APBA1 Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-EASHPSQDGKRQYK corresponding to internal region according to NP_001154.2.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for APBA1 Antibody

Western Blot: APBA1 Antibody [NBP1-06015]

Western Blot: APBA1 Antibody [NBP1-06015]

Western Blot: APBA1 Antibody [NBP1-06015] - (0.1ug/ml) staining of Human Brain (Cerebellum) 35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for APBA1 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:16000

Western Blot

0.1 - 0.3 ug/ml
Application Notes
WB: Approx. 100 kDa band observed in human brain (cerebellum and hippocampus) lysates (calculated MW of 92.9 kDa band according to NP_001154.2).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: APBA1

The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. [provided by RefSeq]

Alternate Names

Adapter protein X11alpha, amyloid beta (A4) precursor protein-binding, family A, member 1, amyloid beta A4 precursor protein-binding family A member 1, D9S411Eadaptor protein X11alpha, LIN10, mint-1, MINT1amyloid beta (A4) precursor protein-binding, family A, member 1 (X11), Neuronal Munc18-1-interacting protein 1, Neuron-specific X11 protein, phosphotyrosine-binding/-interacting domain (PTB)-bearing protein, UROP11, X11A, X11X11ALPHA

Entrez Gene IDs

320 (Human); 319924 (Mouse); 83589 (Rat)

Gene Symbol

APBA1

UniProt

NP_001154.2 (Human)

Additional APBA1 Products

Product Documents for APBA1 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for APBA1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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