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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry

Label

CoraFluor 1

Antibody Source

Monoclonal Mouse IgG2B Clone # 354008

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human APLP-1
Gln34-Glu580 (predicted)
Accession # P51693

Specificity

Detects human APLP-1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, 100% cross‑reactivity with recombinant mouse APLP‑1 is observed and no cross-reactivity with recombinant human APLP‑2 is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Description

CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.

Applications for APLP-1 Antibody (354008) [CoraFluor™ 1]

Application
Recommended Usage

Immunocytochemistry

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark. Do not freeze.

Background: APLP-1

APLP1, or Amyloid-like protein 1, contains two similar isoforms weighing approximately 72 kDa each, and is involved in postsynaptic function and signal transduction activation. Disease research is currently being conducted on APLP1 and its relation to chronic fatigue syndrome, lissencephaly, neuronitis, infertility, neurodegeneration, pharyngitis, cerebritis, and neuroblastoma. The protein is not linked to specific pathways, but it does interact with ZNF24, TK1, TSC22D1, EEF1A1, and GDF9.

Long Name

Amyloid-like Protein 1

Alternate Names

APLP1

Gene Symbol

APLP1

Additional APLP-1 Products

Product Documents for APLP-1 Antibody (354008) [CoraFluor™ 1]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for APLP-1 Antibody (354008) [CoraFluor™ 1]

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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